… Dirofilaria immitis is a … immitis in dogs can help the adoption of control measures that aim
to reduce the occurrence of parasitosis in animals and humans. The detection of D. immitis is …

… The clinical validation of the molecular markers for ML resistance in D. immitis provides the
rst genetic test to con rm … These markers can be used to differentiate between ML-resistant D. …

… Dirofilaria immitis populations are heterologous and can have a high degree of genetic
variability within a population of an isolate within an individual host. ML resistance, as it is …

… for genetic markers). Haplotype Di1 was the dominant haplotype encompassing 91 of the
122 sequences (75%), from all nine countries and four host species (Fig. 1; Additional file 1: …

… Dirofilaria immitis infection is one of the most severe parasitic diseases in dogs. Prevention
is … immitis [47], led to the identification of genetic markers apparently associated with ML …

… Dirofilaria immitis causes pulmonary and cardiopulmonary dirofilariosis in humans and
dogs, … if it was positive for: (i) at least one of the molecular markers of heartworm (DNA of D. …

… adult worms of Dirofilaria immitis (a) and posterior end of a male Dirofilaria immitis showing
… Providing additional genetic markers as well as obtaining more isolates from various …

… Dirofilaria immitis, the canine heartworm, is an important filarial nematode that typically
inhabits the right ventricle and pulmonary arteries of its hosts. It can cause infections in dogs, cats…

… Microsatellites are highly polymorphic molecular markers consisting of tandemly
repeating DNA sequence motifs that range in length from 1 to 8 nucleotides. The suitability of …

… heartworm disease, caused by Dirofilaria immitis, relies on macrocyclic lactones for which
drug resistance is now a concern. Although genetic … and reliable genetic markers that are …