Molecular mechanisms of the acute kidney injury to chronic kidney disease transition: an updated view

F Guzzi, L Cirillo, RM Roperto, P Romagnani… - … journal of molecular …, 2019 - mdpi.com
… link between acute kidney injury (AKI) and chronic kidney disease (CKD… molecular
mechanisms, behind the ability of a single, acute, apparently self-limiting event to drive chronic …

Covid‐19 and kidney injury: Pathophysiology and molecular mechanisms

E Ahmadian, SM Hosseiniyan Khatibi… - Reviews in medical …, 2021 - Wiley Online Library
mechanisms of AKI. Moreover, lower oxygen delivery … kidney may cause an ischaemic
injury. Understanding the fundamental molecular pathways and pathophysiology of kidney injury

Cellular and molecular mechanisms of kidney fibrosis

S Djudjaj, P Boor - Molecular aspects of medicine, 2019 - Elsevier
… process common to any ongoing, chronic kidney injury or maladaptive repair. It is considered
as the underlying pathological process of chronic kidney disease (CKD), which affects …

[HTML][HTML] Molecular mechanisms and therapeutic targets for diabetic kidney disease

KR Tuttle, R Agarwal, CE Alpers, GL Bakris… - Kidney international, 2022 - Elsevier
… In this review, a current understanding of molecular mechanisms that drive DKD … acute
kidney injury may promote transition to chronic injury. The potential role of macrophages in kidney

[HTML][HTML] The ageing kidney: Molecular mechanisms and clinical implications

Y Fang, AY Gong, ST Haller, LD Dworkin, Z Liu… - Ageing research …, 2020 - Elsevier
… Although ageing per se does not cause kidney injury, physiologic changes … of kidney ageing,
the cellular and molecular mechanisms responsible for age-related processes in the kidney

Identifying common molecular mechanisms in experimental and human acute kidney injury

LMS Gerhardt, AP McMahon - Seminars in nephrology, 2022 - Elsevier
… Animal models have greatly enhanced our understanding of the molecular mechanisms
underlying AKI and many features of both adaptive and maladaptive renal repair are conserved …

[HTML][HTML] Understanding kidney injury molecule 1: a novel immune factor in kidney pathophysiology

J Song, J Yu, GW Prayogo, W Cao, Y Wu… - American journal of …, 2019 - ncbi.nlm.nih.gov
… TIM1 is a co-stimulator of T cell activation that regulates the innate and adaptive immune
system via related molecular mechanisms [4]. Thus there is a potential link between HAVCR1/…

Molecular nephrology: types of acute tubular injury

B Desanti De Oliveira, K Xu, TH Shen… - Nature Reviews …, 2019 - nature.com
… Our understanding of the molecular responses to kidney injury will continue to develop with
the application of tools including histopathology, single cell analyses, novel methods of RNA …

[HTML][HTML] Mechanisms and therapeutic targets of ischemic acute kidney injury

SJ Han, HT Lee - Kidney research and clinical practice, 2019 - ncbi.nlm.nih.gov
molecules. Many studies reported that blocking or genetic deletion of these adhesion molecules
protect against kidney injury in … to further endothelial cell injury and dysregulation of the …

Role of damage-associated molecular patterns in septic acute kidney injury, from injury to recovery

PO Ludes, C De Roquetaillade… - Frontiers in …, 2021 - frontiersin.org
… DAMPs in sepsis-induced acute kidney injury and therapeutic perspectives. DAMPs are …
kidney injury and kidney fibrosis. The secretion of DAMPs is the result of different mechanisms of …