Ruscogenin attenuates sepsis-induced acute lung injury and pulmonary endothelial barrier dysfunction via TLR4/Src/p120-catenin/VE-cadherin signalling pathway
Y Wang, L Xue, Y Wu, J Zhang, Y Dai… - Journal of Pharmacy …, 2021 - academic.oup.com
… of VE-cadherin and maintains endothelial barrier function. [41] Decreased expression of
pulmonary VE-cadherin and p120-catenin were observed in animal models of sepsis-induced …
pulmonary VE-cadherin and p120-catenin were observed in animal models of sepsis-induced …
[HTML][HTML] Protocadherin 20 maintains intestinal barrier function to protect against Crohn's disease by targeting ATF6
S Huang, Z Xie, J Han, H Wang, G Yang, M Li, G Zhou… - Genome Biology, 2023 - Springer
… In this study, we describe a critical role for PCDH20 in maintaining intestinal homeostasis.
Intestinal-… However, we detected only the T310 and S288 phosphosites of p120-catenin as no …
Intestinal-… However, we detected only the T310 and S288 phosphosites of p120-catenin as no …
[HTML][HTML] E-cadherin beyond structure: a signaling hub in colon homeostasis and disease
AC Daulagala, MC Bridges, A Kourtidis - International journal of …, 2019 - mdpi.com
… , namely p120 catenin (p120), α-catenin, and β-catenin [2]. Nectin is another important cell-cell
… diabetes and hyperglycemia negatively impact intestinal barrier function, which, in turn, …
… diabetes and hyperglycemia negatively impact intestinal barrier function, which, in turn, …
Trans-compartmental regulation of tight junction barrier function
AN Naser, Q Lu, YH Chen - Tissue Barriers, 2023 - Taylor & Francis
… , demonstrating disruption of the intestinal barrier function. This study highlights the essential
role of p120 ctn in maintaining TJ barrier function and intestinal homeostasis. Citation34 …
role of p120 ctn in maintaining TJ barrier function and intestinal homeostasis. Citation34 …
[HTML][HTML] EpCAM is essential for maintenance of the small intestinal epithelium architecture via regulation of the expression and localization of proteins that compose …
G Chen, Y Yang, W Liu, L Huang… - International …, 2021 - spandidos-publications.com
… intestines, and is essential for maintaining the homeostasis of the intestinal epithelium…
EpCAM protein is localized at tight junctions and the basolateral membrane of the intestinal …
EpCAM protein is localized at tight junctions and the basolateral membrane of the intestinal …
[HTML][HTML] Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases
LR Lessey, SC Robinson, R Chaudhary… - Frontiers in Cell and …, 2022 - frontiersin.org
… cofactors (α, β, γ, and p120-catenin). One organ where … essential for normal intestinal
homeostasis, studies from our lab and others have explored Kaiso’s role in the mammalian intestine…
homeostasis, studies from our lab and others have explored Kaiso’s role in the mammalian intestine…
P120-catenin regulates pulmonary fibrosis and TGF-β induced lung fibroblast differentiation
Y Zhang, H Jiao, Y Wu, X Sun - Life sciences, 2019 - Elsevier
… P120-catenin (P120) was known to function in adhesion between cells and signal transduction
in many types of cells. In this study, we investigated the expression and role of P120 in …
in many types of cells. In this study, we investigated the expression and role of P120 in …
p120-Catenin suppresses NLRP3 inflammasome activation in macrophages
P Kanmani, HEH Elkafas, M Ghazal… - … of Physiology-Lung …, 2023 - journals.physiology.org
… Here we investigated the role of p120-catenin expression in … Depletion of p120-catenin
in murine bone marrow-derived … Coimmunoprecipitation analysis showed that p120-catenin …
in murine bone marrow-derived … Coimmunoprecipitation analysis showed that p120-catenin …
[HTML][HTML] Differential expression of p120-catenin 1 and 3 isoforms in epithelial tissues
… p120-catenin is essential for maintenance of barrier function and intestinal homeostasis
in mice. J Clin Invest 120, 1824–1835, https://doi.org/10.1172/JCI41414 (2010). …
in mice. J Clin Invest 120, 1824–1835, https://doi.org/10.1172/JCI41414 (2010). …
ROCK1 inhibitor stabilizes E-cadherin and improves barrier function in experimental necrotizing enterocolitis
C Buonpane, C Yuan, D Wood… - … -Gastrointestinal …, 2020 - journals.physiology.org
… maintaining normal barrier homeostasis. Rho-associated protein kinase-1 (ROCK1) is a kinase
that regulates the E-cadherin complex, and p120-catenin is … gastrointestinal homeostasis. …
that regulates the E-cadherin complex, and p120-catenin is … gastrointestinal homeostasis. …