[HTML][HTML] … iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and …
JM Oh, BC Ahn - Theranostics, 2021 - ncbi.nlm.nih.gov
The advanced, metastatic differentiated thyroid cancers (DTCs) have a poor prognosis
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …
[HTML][HTML] Signal pathway of estrogen and estrogen receptor in the development of thyroid cancer
J Liu, T Xu, L Ma, W Chang - Frontiers in oncology, 2021 - frontiersin.org
… ) signal pathway due to mutations are critical in cancer progression. This review summarizes
the pathways involved in the molecular mechanisms of estrogen and ER in thyroid cancer, …
the pathways involved in the molecular mechanisms of estrogen and ER in thyroid cancer, …
[HTML][HTML] New therapies for advanced thyroid cancer
D Laha, N Nilubol, M Boufraqech - Frontiers in endocrinology, 2020 - frontiersin.org
… pathways in thyroid cancer and to discuss the most recent targeted therapies and
immunotherapy for advanced thyroid cancer with a promising anti-tumor activity and clinical benefit. …
immunotherapy for advanced thyroid cancer with a promising anti-tumor activity and clinical benefit. …
[HTML][HTML] Vitamin C kills thyroid cancer cells through ROS-dependent inhibition of MAPK/ERK and PI3K/AKT pathways via distinct mechanisms
… the antitumor activity of vitamin C in thyroid cancer. … thyroid cancer 14 . We, therefore,
attempted to explore the effect of vitamin C on the activities of these two pathways in thyroid cancer …
attempted to explore the effect of vitamin C on the activities of these two pathways in thyroid cancer …
[HTML][HTML] Baicalein induced apoptosis and autophagy of undifferentiated thyroid cancer cells by the ERK/PI3K/Akt pathway
M Wang, S Qiu, J Qin - American journal of translational research, 2019 - ncbi.nlm.nih.gov
… /Akt pathways. In conclusion, baicalein could suppress the growth of undifferentiated thyroid
cancer … The inhibition of the ERK and PI3K/Akt pathways may be involved in the mechanism. …
cancer … The inhibition of the ERK and PI3K/Akt pathways may be involved in the mechanism. …
Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways
… Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the
Papillary thyroid cancer (PTC)(most common and follicular thyroid … signaling pathways such …
Papillary thyroid cancer (PTC)(most common and follicular thyroid … signaling pathways such …
[HTML][HTML] Update on fundamental mechanisms of thyroid cancer
A Prete, P Borges de Souza, S Censi… - Frontiers in …, 2020 - frontiersin.org
… The molecular pathogenesis of thyroid cancer involves dysregulation of the mitogen-… (PI3K)/AKT
pathways. Common activating mutations in the MAPK pathway include RET-PTC and …
pathways. Common activating mutations in the MAPK pathway include RET-PTC and …
[HTML][HTML] The role of microRNAs in the pathogenesis of thyroid cancer
… the activity of thyroid cancer-related signaling pathways such as MAPK pathway and RET …
have differential expression in different stages of thyroid cancer. Assessment of serum levels of …
have differential expression in different stages of thyroid cancer. Assessment of serum levels of …
[HTML][HTML] Molecular alterations in thyroid cancer: from bench to clinical practice
E Tirrò, F Martorana, C Romano, SR Vitale, G Motta… - Genes, 2019 - mdpi.com
… detected in thyroid cancer, we will initially discuss RTK-related upstream signaling pathways
involved in tumorigenesis and subsequently focus on the effectors of these pathways. …
involved in tumorigenesis and subsequently focus on the effectors of these pathways. …
[HTML][HTML] Recent advances in the management of anaplastic thyroid cancer
S De Leo, M Trevisan, L Fugazzola - Thyroid research, 2020 - Springer
… )/AKT/mTOR pathway has been reported in thyroid cancer pathogenesis. Everolimus is a
Sirolimus-derived mTOR inhibitor, whose activity against several thyroid cancer cell lines has …
Sirolimus-derived mTOR inhibitor, whose activity against several thyroid cancer cell lines has …
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