[HTML][HTML] Pathophysiology in patients with polytrauma

HC Pape, EE Moore, T Mckinley, A Sauaia - Injury, 2022 - Elsevier
… of hypoperfusion are most relevant due to the endothelial permeability changes, it was
discovered that the innate immune response to trauma is equally important in modifying the organ …

Management of aesthetic and functional deficits in frontal bone trauma

M Dumitru, D Vrinceanu, B Banica, R Cergan, IA Taciuc… - Medicina, 2022 - mdpi.com
… are necessary but maintain FND permeability [23]. Displaced … reconstruction of the defects
using metal plates (Figure 7). … Moreover, the team caring for the trauma patient should be as …

Why are bleeding trauma patients still dying? Towards a systems hypothesis of trauma

GP Dobson, JL Morris, HL Letson - Frontiers in physiology, 2022 - frontiersin.org
trauma patient requires emergent surgery, the body is further stressed by the next surge of
damage signals from the trauma … A better understanding on why bleeding trauma patients are …

Traumatic-induced coagulopathy as a systems failure: a new window into hemostasis

GP Dobson, JL Morris, LM Davenport… - … in Thrombosis and …, 2020 - thieme-connect.com
… 310 trauma patients had delayed platelet activation in the PFA-100 test, suggesting a defect
… of membrane potential, opening of the mitochondrial permeability transition pore, Ca 2+ …

[HTML][HTML] A narrative review of changes in microvascular permeability after burn

Y Chi, X Liu, J Chai - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
… components of the vascular endothelium of trauma patients fall off and the colloidal osmotic
… and thrombin loss after trauma, which affects permeability and coagulation function (26). …

[HTML][HTML] Platelet dysfunction after trauma: From mechanisms to targeted treatment

PH Sloos, P Vulliamy, C van't Veer, AS Gupta… - Transfusion, 2022 - ncbi.nlm.nih.gov
… , and increased permeability are present early after trauma and … based on the patient‐specific
coagulation defects. Early … To improve the care of severely injured trauma patients, …

… , blood–brain barrier permeability, or cognitive outcome in global inducible high mobility group box 1 knockout mice despite tissue sparing after experimental traumatic …

RK Aneja, AM Alcamo, J Cummings, V Vagni… - Journal of …, 2019 - liebertpub.com
… However, we did not observe a significant benefit on post-traumatic brain edema and
BBB permeability, contrasting prior reports. Our data suggest that HMGB1 may be a dual-edged …

Vascular permeability in diseases

JL Wautier, MP Wautier - International Journal of Molecular Sciences, 2022 - mdpi.com
permeability is responsible for major complications. Since we have substantial research in
diabetes mellitus patients, in … Various brain diseases, traumatic brain injury, and stroke can be …

Strategies for re-vascularization and promotion of angiogenesis in trauma and disease

RC Gonçalves, A Banfi, MB Oliveira, JF Mano - Biomaterials, 2021 - Elsevier
permeability through paracellular-mediated transport between ECs, that highly depends
on organ's functions [26,27]. For instance, the blood-brain-barrier has low permeability

Beyond the brain: peripheral interactions after traumatic brain injury

SJ McDonald, JM Sharkey, M Sun… - Journal of …, 2020 - liebertpub.com
patients requiring admission to intensive care similarly show increased intestinal permeability,
… Increased intestinal permeability results in endotoxemia attributed to translocation of gut …