The role of PI3K/Akt and ERK in neurodegenerative disorders

SN Rai, H Dilnashin, H Birla, SS Singh, W Zahra… - Neurotoxicity …, 2019 - Springer
… Some of these components are cytosolic targets of ERK, thus implicating MAPK pathway
in formation/maintenance of such pathological hallmark, and therefore in the noxious events …

Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways

X Liang, Y Ding, F Lin, Y Zhang, X Zhou… - The FASEB …, 2019 - Wiley Online Library
… Inhibition of PI3K/AKT or MAPK/ERK pathway greatly increased cell senescence in … and the
effect of PI3K/AKT pathway was more prominent than MAPK/ERK pathway (Supplemental Fig…

[HTML][HTML] ENKUR acts as a tumor suppressor in lung adenocarcinoma cells through PI3K/Akt and MAPK/ERK signaling pathways

Q Ma, Y Lu, J Lin, Y Gu - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
… to several TRPC proteins and the p85 subunit of PI3K. However, the role of ENKUR in cancer
PI3K directly and is possibly involved in the PI3K/Akt and MAPK/ERK signaling pathways. …

The role of PI3K/AKT and MAPK signaling pathways in erythropoietin signalization

Z Tóthová, M Šemeláková, Z Solárová, J Tomc… - International Journal of …, 2021 - mdpi.com
… Another mechanism of retinal cytoprotection via maintaining zinc homeostasis by the
EPOR/MAPK ERK pathway and upregulation of ZnT8 expression was also demonstrated [110]. …

Green barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways

BE Ruiz-Medina, D Lerma, M Hwang, JA Ross… - Scientific reports, 2019 - nature.com
pathway that can be activated by Lyn is MAPK/ERK, also involved in cell proliferation,
differentiation, and survival 49,60 . MAPK/ERK … Also, both the MAPK/ERK and the PI3K/Akt

TBX1 functions as a tumor suppressor in thyroid cancer through inhibiting the activities of the PI3K/AKT and MAPK/ERK pathways

N Wang, Y Li, J Wei, J Pu, R Liu, Q Yang, H Guan… - Thyroid, 2019 - liebertpub.com
… Most of these events are strongly associated with over-activation of the PI3K/AKT and
MAPK/ERK … targets, thereby inhibiting the activities of the PI3K/AKT and MAPK/ERK cascades. …

[HTML][HTML] AKT and ERK dual inhibitors: the way forward?

Z Cao, Q Liao, M Su, K Huang, J Jin, D Cao - Cancer letters, 2019 - Elsevier
PI3K/AKT and MAPK/ERK pathways are dysregulated in almost one-third of human cancers,
and in many cancers, the PI3K/AKT and MAPK/ERK … in PI3K/AKT and MAPK/ERK targeted …

Allicin attenuates pathological cardiac hypertrophy by inhibiting autophagy via activation of PI3K/Akt/mTOR and MAPK/ERK/mTOR signaling pathways

L Ba, J Gao, Y Chen, H Qi, C Dong, H Pan, Q Zhang… - Phytomedicine, 2019 - Elsevier
… And it could be regulated by PI3K/Akt and MAPK/ERK signaling pathways. Especially,
mTOR activation by PI3K/Akt and MAPK/ERK signaling pathways could inhibit excessive …

[HTML][HTML] Assessment of PI3K/AKT and MAPK/ERK pathways activation in oral lymphatic malformations

IP Gomes, LM Guimarães, TSF Pereira… - Oral Surgery, Oral …, 2022 - Elsevier
… activation of PI3K/AKT and MAPK/ERK signaling pathways … the activation of MAPK/ERK and
PI3K/AKT signaling pathways … The activation of PI3K/AKT and MAPK/ERK observed in oral …

Fucoidan induces apoptosis and inhibits proliferation of hepatocellular carcinoma via the p38 MAPK/ERK and PI3K/Akt signal pathways

Y Duan, J Li, X Jing, X Ding, Y Yu… - Cancer Management and …, 2020 - Taylor & Francis
… The capability of fucoidan to inhibit the growth of LM3 cells was investigated by monitoring
of the p38 MAPK/ERK pathways and the upstream kinases, PI3K/Akt. LM3 xenograft tumors …