Recently registered midazolam doses for preterm neonates do not lead to equal exposure: a population pharmacokinetic model

S Völler, RB Flint, F Beggah, I Reiss… - The Journal of …, 2019 - Wiley Online Library
… developed a population pharmacokinetic model for midazolam in preterm neonates with a
… was it possible to develop a population pharmacokinetic model of this drug. Although the …

Population pharmacokinetics of sildenafil in extremely premature infants

…, Best Pharmaceuticals for Children Act … - British journal of …, 2019 - Wiley Online Library
… In cohort 1, we obtained PK samples from infants receiving sildenafil as ordered per the local
… of sildenafil and performed PK sampling. We performed a population PK analysis and dose-…

Population pharmacokinetics and dosing optimization of amoxicillin in neonates and young infants

BH Tang, YE Wu, C Kou, YJ Qi, H Qi… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… a few preterm neonates. Thus, we aimed to evaluate the population pharmacokinetics of …
size covering the entire age range of neonates and young infants and to establish evidence-…

Population pharmacokinetics and dosing optimization of latamoxef in neonates and young infants

H Qi, C Kou, YJ Qi, BH Tang, YE Wu, F Jin… - International journal of …, 2019 - Elsevier
population PK in neonates and young infants (n = 128). It established an evidence-based
dosing scheme for this population using developmental PK… is optimal for population PK data …

Preterm physiologically based pharmacokinetic model. Part II: applications of the model to predict drug pharmacokinetics in the preterm population

K Abduljalil, X Pan, A Pansari, M Jamei… - … Pharmacokinetics, 2020 - Springer
… PBPK models combine demographic, genetic, physiological and pathological information
in adults with in vitro data on human drug metabolism and transport to predict population PK

Population pharmacokinetics and dose optimization of vancomycin in neonates

SM Lee, S Yang, S Kang, MJ Chang - Scientific reports, 2021 - nature.com
pharmacokinetics of vancomycin vary among neonates, and we aimed to conduct population
pharmacokinetic … of vancomycin in Korean neonates. From a retrospective chart review, …

Optimizing vancomycin dosing and monitoring in neonates and infants using population pharmacokinetic modeling

P Jarugula, A Akcan-Arikan… - Antimicrobial agents …, 2022 - Am Soc Microbiol
… a vancomycin population PK model for neonates and infants, … evaluation of vancomycin
PK in neonates and infants to our … in this study best predicts PK of our data compared to the …

Population pharmacokinetics of teicoplanin in preterm and term neonates: is it time for a new dosing regimen?

A Kontou, K Sarafidis, O Begou, HG Gika… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
… to develop a population pharmacokinetic (PK) model in … preterm neonates. By using an
optimal design approach, a prospective PK study was designed and implemented in 60 neonates

Effects of maturation and size on population pharmacokinetics of pentoxifylline and its metabolites in very preterm infants with suspected late‐onset sepsis or …

S Salman, J Hibbert, M Page‐Sharp… - British journal of …, 2019 - Wiley Online Library
… In summary, this report presents the first population pharmacokinetic model of PTX and its
principal metabolites and indicates that preterm infants' elimination capacity matures rapidly …

External Evaluation of Population Pharmacokinetic Models of Piperacillin in Preterm and Term Patients from Neonatal Intensive Care

FS Boer-Pérez, V Lima-Rogel… - … and Pharmacokinetics, 2024 - Springer
… models allows us to select the most adapted model for our population [27,28,29]. … population
pharmacokinetic models for piperacillin in neonates using clinical data collected for preterm