A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?
X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
… Hydrogen sulfide (H 2 S) is a colorless gas characterized with a strong rotten egg smell
under … Usually, the intoxication of H 2 S is ascribed to its strong suppressive effect on several …
under … Usually, the intoxication of H 2 S is ascribed to its strong suppressive effect on several …
[HTML][HTML] Hydrogen sulfide in pharmacotherapy, beyond the hydrogen sulfide-donors
E Zaorska, L Tomasova, D Koszelewski, R Ostaszewski… - Biomolecules, 2020 - mdpi.com
… of endogenous hydrogen sulfide. In this work, we review data regarding sulfur drugs …
Notably, a clinical study showed a greater potency of Remikiren to lower blood pressure in …
Notably, a clinical study showed a greater potency of Remikiren to lower blood pressure in …
Modulation of the functions of myeloid‐derived suppressor cells: a new strategy of hydrogen sulfide anti‐cancer effects
P De Cicco, G Ercolano, V Rubino… - British Journal of …, 2020 - Wiley Online Library
… In this study, we assessed the ability of hydrogen sulfide (H 2 S), a gasotransmitter whose
anti‐cancer effects are well known, to inhibit the accumulation and immunosuppressive …
anti‐cancer effects are well known, to inhibit the accumulation and immunosuppressive …
[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system
N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes - …
mammals. It is produced by mammalian cells and tissues by various enzymes - …
Activatable small-molecule hydrogen sulfide donors
Significance: Hydrogen sulfide (H 2 S) is an important biological signaling molecule involved
in many physiological processes. These diverse roles have led researchers to develop …
in many physiological processes. These diverse roles have led researchers to develop …
Hydrogen sulfide donors: Therapeutic potential in anti-atherosclerosis
H Zhang, Z Bai, L Zhu, Y Liang, X Fan, J Li… - European Journal of …, 2020 - Elsevier
… Hydrogen sulfide (H 2 S) was discovered as the third gaseous signaling molecule following
nitric oxide (NO) and carbon monoxide (CO), and has been proposed to exert potentially …
nitric oxide (NO) and carbon monoxide (CO), and has been proposed to exert potentially …
Effects of hydrogen sulfide on the microbiome: from toxicity to therapy
… Indeed, microbial adhesion to and invasion through the host epithelium trigger potent … further
support of the importance of H 2 S as a modulator of microbial biofilms (75). However, there …
support of the importance of H 2 S as a modulator of microbial biofilms (75). However, there …
Anti‐inflammatory and antiviral roles of hydrogen sulfide: Rationale for considering H2S donors in COVID‐19 therapy
V Citi, A Martelli, V Brancaleone, S Brogi… - British journal of …, 2020 - Wiley Online Library
… In the last decades, the endogenous gasotransmitter hydrogen sulfide (H 2 S) has emerged
as modulator of several biological functions and its deficiency has been associated with …
as modulator of several biological functions and its deficiency has been associated with …
[HTML][HTML] Hydrogen sulfide, an endogenous stimulator of mitochondrial function in cancer cells
C Szabo - Cells, 2021 - mdpi.com
Hydrogen sulfide (H 2 S) has a long history as toxic gas and environmental hazard; inhibition
of cytochrome c oxidase (mitochondrial Complex IV) is viewed as a primary mode of its …
of cytochrome c oxidase (mitochondrial Complex IV) is viewed as a primary mode of its …
SG1002 and catenated divalent organic sulfur compounds as promising hydrogen sulfide prodrugs
G Gojon, GA Morales - Antioxidants & Redox Signaling, 2020 - liebertpub.com
… Sulfur has a critical role in protein structure/function and redox status/signaling in all living
organisms. Although hydrogen sulfide (H 2 S) and sulfane sulfur … depth of sulfur metabolome's …
organisms. Although hydrogen sulfide (H 2 S) and sulfane sulfur … depth of sulfur metabolome's …
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