Application of prostate cancer models for preclinical study: advantages and limitations of cell lines, patient-derived xenografts, and three-dimensional culture of patient …

T Namekawa, K Ikeda, K Horie-Inoue, S Inoue - Cells, 2019 - mdpi.com
… Since the development of the HeLa cell line, several cancer cell lines have been … cancer
tumorigenesis and for identifying markers of therapeutic response [30]. Cancer cell lines are …

The need for cell lines from diverse ethnic backgrounds for prostate cancer research

S Badal, KS Campbell, H Valentine, C Ragin - Nature Reviews Urology, 2019 - nature.com
… to create a diverse panel of prostate cancer cell lines. A novel panel of six prostate cancer
cell lines consisting of three lines from MAA and three lines from MEA aided the discovery of …

The transcription factor ZEB1 promotes chemoresistance in prostate cancer cell lines

O Orellana-Serradell, D Herrera… - Asian journal of …, 2019 - journals.lww.com
… main chemotherapeutic used in advanced prostate cancer treatment. The mechanisms involved
… in prostate cancer cell lines. In this work, we used prostate cancer cell lines 22Rv1 and …

The synergistic effects of betanin and radiotherapy in a prostate cancer cell line: an in vitro study

S Montazersaheb, S Jafari, MD Aytemir… - Molecular Biology …, 2023 - Springer
… A major limitation of our study is using only one cell line of prostate cancer. Also, to better
understand the underlying mechanisms of betanin and RT in treating PCa, further in vivo …

Development of machine learning classifiers to predict compound activity on prostate cancer cell lines

D Bonanni, L Pinzi, G Rastelli - Journal of Cheminformatics, 2022 - Springer
Prostate cancer is the most common type of cancercell-based antiproliferative assay data,
able to predict the activity of ligands towards the PC-3 and DU-145 prostate cancer cell lines. …

Concentration-dependent effects of zinc sulfate on DU-145 human prostate cancer cell line: oxidative, apoptotic, inflammatory, and morphological analyzes

C Hacioglu, S Kacar, F Kar, G Kanbak… - Biological trace element …, 2020 - Springer
… Also, it was reported that zinc induces apoptosis in prostate cancer cell lines unlike normal
prostate cells [26]. Although, in the current study, zinc treatments were greater than plasma …

Resveratrol inhibits DHT-induced progression of prostate cancer cell line through interfering with the AR and CXCR4 pathway

YG Jang, RE Go, KA Hwang, KC Choi - The Journal of steroid biochemistry …, 2019 - Elsevier
… In addition, the roles of Res as dual antagonists against AR and CXCR4 were also examined
in the present study in order to identify its anti-prostate cancer activity as well as suggest it …

Vaccinium myrtillus L. extract and its native polyphenol‐recombined mixture have anti‐proliferative and pro‐apoptotic effects on human prostate cancer cell lines

M Del Bubba, C Di Serio, L Renai… - Phytotherapy …, 2021 - Wiley Online Library
… that PrEC are more resistant than PCa cell lines. VME also reduced the anchorage-… +late)
was statistically higher in all three cell lines exposed to VME compared to control. Anchorage-…

… expression of protein disulfide-isomerase A3 isoforms, PDIA3 and PDIA3N, in human prostate cancer cell lines representing different stages of prostate cancer

MA Diaz Cruz, S Karlsson, F Szekeres… - Molecular Biology …, 2021 - Springer
prostate cell lines, in line with previous studies on kidney and colon cells where PDIA3N is
associated with cancer … expression compared to PDIA3 in prostate cells with especially high …

Dual effect of tryptamine on prostate cancer cell growth regulation: a pilot study

Z Li, B Ding, MRK Ali, L Zhao, X Zang, Z Lv - International Journal of …, 2022 - mdpi.com
… PC-3 and LNCaP, stronger than those on the normal prostate cell line RWPE-1. … two PCa
cell lines were also more sensitive to tryptamine compared with the other three cancer cell lines