Current and emerging therapies for metastatic castration-resistant prostate cancer (mCRPC)
… Prostate cancer (PCa) is one of the most common cancers in men. In the year 2020, an …
-resistant prostate cancer (mCRPC). The long-term prognosis for patients with mCRPC is poor, …
-resistant prostate cancer (mCRPC). The long-term prognosis for patients with mCRPC is poor, …
Update on systemic prostate cancer therapies: management of metastatic castration-resistant prostate cancer in the era of precision oncology
P Nuhn, JS De Bono, K Fizazi, SJ Freedland, M Grilli… - European urology, 2019 - Elsevier
… the management of advanced prostate cancer provides a range of treatment options with
notable benefits for men with metastatic castration-resistant prostate cancer (mCRPC). At the …
notable benefits for men with metastatic castration-resistant prostate cancer (mCRPC). At the …
[HTML][HTML] Current therapy and drug resistance in metastatic castration-resistant prostate cancer
M Cai, XL Song, XA Li, M Chen, J Guo, DH Yang… - Drug Resistance …, 2023 - Elsevier
… of mCRPC. In order to help comprehensively understand latest advances in the treatment …
mCRPC and the mechanisms of drug resistance, we summarize current therapies for mCRPC …
mCRPC and the mechanisms of drug resistance, we summarize current therapies for mCRPC …
[HTML][HTML] Prostate-specific membrane antigen heterogeneity and DNA repair defects in prostate cancer
A Paschalis, B Sheehan, R Riisnaes, DN Rodrigues… - European urology, 2019 - Elsevier
… DDR = defective DNA repair; FPKM = Fragments Per Kilobase of transcript per Million
mapped reads; mCRPC = metastatic castration-resistant prostate cancer; PSMA = …
mapped reads; mCRPC = metastatic castration-resistant prostate cancer; PSMA = …
Real-world treatment patterns and overall survival among men with Metastatic Castration-Resistant Prostate Cancer (mCRPC) in the US Medicare population
… of metastatic castration-resistant prostate cancer (mCRPC), increasing options available to
… of men with mCRPC. Toward this effort, recent studies evaluated mCRPC treatment patterns …
… of men with mCRPC. Toward this effort, recent studies evaluated mCRPC treatment patterns …
Real-world outcomes in first-line treatment of metastatic castration-resistant prostate cancer: the prostate cancer registry
S Chowdhury, A Bjartell, N Lumen, P Maroto, T Paiss… - Targeted Oncology, 2020 - Springer
… Prospective, noninterventional analysis of patient record data in the multicenter Prostate
Cancer Registry (PCR) of men with mCRPC. The data were collected in 16 countries with the …
Cancer Registry (PCR) of men with mCRPC. The data were collected in 16 countries with the …
[HTML][HTML] Past, current, and future of immunotherapies for prostate cancer
AN Boettcher, A Usman, A Morgans… - Frontiers in …, 2019 - frontiersin.org
… metastatic castration-resistant prostate cancer (mCRPC), of … types of cancer, but only a
marginal benefit for mCRPC, at … nature of the prostate tumor microenvironment, including …
marginal benefit for mCRPC, at … nature of the prostate tumor microenvironment, including …
The effects of new life-prolonging drugs for metastatic castration-resistant prostate cancer (mCRPC) patients in a real-world population
HM Westgeest, MCP Kuppen… - … cancer and prostatic …, 2021 - nature.com
… Eligible patients had to be diagnosed with prostate cancer (defined as histologic confirmation
of prostate cancer or as concluded by the treating doctor based on elevated PSA and …
of prostate cancer or as concluded by the treating doctor based on elevated PSA and …
Pharmacotherapeutic strategies for castrate-resistant prostate cancer
M Moussa, A Papatsoris, M Abou Chakra… - Expert opinion on …, 2020 - Taylor & Francis
… Metastatic castration-resistant prostate cancer (mCRPC) spreads quickly and does not
respond to surgical or medical castration. It is defined as serum testosterone level <50 ng/dL …
respond to surgical or medical castration. It is defined as serum testosterone level <50 ng/dL …
[HTML][HTML] Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions
RJ Scott, A Mehta, GS Macedo, PS Borisov… - Oncotarget, 2021 - ncbi.nlm.nih.gov
… Metastatic castration-resistant prostate cancer (mCRPC) is a latestage … , mCRPC still
remains a lethal disease. Identification of specific novel predictive biomarker mutations in mCRPC …
remains a lethal disease. Identification of specific novel predictive biomarker mutations in mCRPC …
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