Mechanism of anti-cancer activity of curcumin on androgen-dependent and androgen-independent prostate cancer

NA Abd. Wahab, N H. Lajis, F Abas, I Othman, R Naidu - Nutrients, 2020 - mdpi.com
… It was shown that curcumin exhibits anti-cancer effect in several tumour models through
regulating PI3K/Akt/mTOR pathway whereby it suppresses the Akt activation along with …

Anti-cancer effects of green tea polyphenols against prostate cancer

Y Miyata, Y Shida, T Hakariya, H Sakai - Molecules, 2019 - mdpi.com
… As mentioned above, EGCG is recognized to have the strongest anti-cancer activity among
… positive PC cells in the prostate tissues of a xenograft model injected with androgen-sensitive …

Synthesis, molecular modeling, in vivo study, and anticancer activity of 1,2,4‐triazole containing hydrazide–hydrazones derived from (S)‐naproxen

Mİ Han, H Bekçi, AI Uba, Y Yıldırım… - Archiv der …, 2019 - Wiley Online Library
modeling of these compounds was studied on human methionine aminopeptidase-2. All
synthesized compounds were screened for anticancer activity against three prostate cancer cell …

Anticancer activity of the plant flavonoid luteolin against preclinical models of various cancers and insights on different signalling mechanisms modulated

SA Ganai, FA Sheikh, ZA Baba, MA Mir… - Phytotherapy …, 2021 - Wiley Online Library
… In a prostate cancer xenograft mouse model, the volume and weight of solid tumors were
markedly reduced on luteolin (10 mg/kg/day) treatment, clearly showing that luteolin restrains …

The anticancer potential of metformin on prostate cancer

S Zaidi, J Gandhi, G Joshi, NL Smith… - … cancer and prostatic …, 2019 - nature.com
… Rodent models had shown that statins induced an antitumor effect through the reduction of
… and radiotherapy enhanced the reduction of prostate tumor growth in mouse models [19]. MF …

Revisiting immunotherapy: a focus on prostate cancer

HR Cha, JH Lee, S Ponnazhagan - Cancer research, 2020 - AACR
… a niche unsuitable for tumor-infiltrating immune cells with antitumor activities, leading to …
results indicate promising outcome with murine prostate cancer model (109). Conventional …

Application of prostate cancer models for preclinical study: advantages and limitations of cell lines, patient-derived xenografts, and three-dimensional culture of patient …

T Namekawa, K Ikeda, K Horie-Inoue, S Inoue - Cells, 2019 - mdpi.com
… Various preclinical models have been developed to clarify the pathophysiology of prostate
cancer (… , and a PI3K/mTOR inhibitor exerts a significant antitumor effect on the PC3CR cells. …

Lycopene exerts anti-inflammatory effect to inhibit prostate cancer progression

LN Jiang, YB Liu, BH Li - Asian journal of andrology, 2019 - journals.lww.com
… agent for prostate cancer. Definitive evidence to support the anticancer effect of lycopene is
prostate cancer tumor models would greatly facilitate the clinical translation of lycopene in …

[HTML][HTML] Past, current, and future of immunotherapies for prostate cancer

AN Boettcher, A Usman, A Morgans… - Frontiers in …, 2019 - frontiersin.org
… ), which enhanced T and NK anti-tumor activity in a preclinical mouse model (76). A
Phase I trial recruiting patients with locally recurrent prostate cancer for Ad5-yCD/mutTKSR39rep-…

Potent in vitro and in vivo anticancer activity of new bipyridine and bipyrimidine gold (III) dithiocarbamate derivatives

M Altaf, N Casagrande, E Mariotto, N Baig, AN Kawde… - Cancers, 2019 - mdpi.com
tumor types. The compounds showed promising anticancer activity in different tumor models
[… This analysis showed that C6 was more potent in the prostate tumor cells (IC 50 = 0.6 μM) …