A prospective single-arm phase 2 study of stereotactic magnetic resonance guided adaptive radiation therapy for prostate cancer: early toxicity results
AME Bruynzeel, SU Tetar, SS Oei, S Senan… - International Journal of …, 2019 - Elsevier
… We performed a prospective phase 2 study of MRgRT for localized prostate cancer to …
studied using both clinician-scored and patient-reported outcomes. A nonrandomized phase 2 …
studied using both clinician-scored and patient-reported outcomes. A nonrandomized phase 2 …
Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial
MR Smith, HI Scher, S Sandhu, E Efstathiou… - The Lancet …, 2022 - thelancet.com
… In this multicentre, open-label, single-arm, phase 2 study, patients aged at least 18 years
with histologically confirmed metastatic castration-resistant prostate cancer (mixed histology …
with histologically confirmed metastatic castration-resistant prostate cancer (mixed histology …
A Phase 2/3 Prospective Multicenter Study of the Diagnostic Accuracy of Prostate Specific Membrane Antigen PET/CT with 18F-DCFPyL in Prostate Cancer Patients …
… tomography to stage men with high-risk prostate cancer for nodal or distant metastases,
and reliably detect sites of disease in men with suspected metastatic prostate cancer. …
and reliably detect sites of disease in men with suspected metastatic prostate cancer. …
Outcomes of observation vs stereotactic ablative radiation for oligometastatic prostate cancer: the ORIOLE phase 2 randomized clinical trial
… This study reports the findings of a phase 2 randomized clinical trial of observation vs
SABR in men … The study also shows the value of the prostate-specific membrane antigen (PSMA)–…
SABR in men … The study also shows the value of the prostate-specific membrane antigen (PSMA)–…
… of enzalutamide and abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase 2, crossover …
DJ Khalaf, M Annala, S Taavitsainen, DL Finch… - The Lancet …, 2019 - thelancet.com
… in two randomised phase 2 studies. In the randomised PLATO study, patients received …
In conclusion, our study showed that abiraterone and enzalutamide have similar first-line …
In conclusion, our study showed that abiraterone and enzalutamide have similar first-line …
[HTML][HTML] … in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 …
… Our results, if confirmed in registration studies, would support the implementation of tumour
… -resistant prostate cancer, we designed TOPARP, an adaptive programme of serial phase 2 …
… -resistant prostate cancer, we designed TOPARP, an adaptive programme of serial phase 2 …
Talazoparib monotherapy in metastatic castration-resistant prostate cancer with DNA repair alterations (TALAPRO-1): an open-label, phase 2 trial
… , this study is the first international phase 2 trial to assess the antitumour activity and tolerability
of talazoparib in men with metastatic castration-resistant prostate cancers with alterations …
of talazoparib in men with metastatic castration-resistant prostate cancers with alterations …
… imaging alone to guide postprostatectomy salvage radiotherapy for prostate cancer (EMPIRE-1): a single centre, open-label, phase 2/3 randomised controlled trial
… study was first conceived and designed in 2011, molecular imaging with PET radiotracers
were not being done routinely for prostate cancer. … matter virtually any imaging study) had not …
were not being done routinely for prostate cancer. … matter virtually any imaging study) had not …
[HTML][HTML] A phase 2 trial of avelumab in men with aggressive-variant or neuroendocrine prostate cancer
LC Brown, S Halabi, JA Somarelli… - … Cancer and Prostatic …, 2022 - nature.com
… )-independent prostate cancer, or anaplastic prostate cancer, … for men with metastatic prostate
cancer. Approximately 20% … , a single-arm phase 2 clinical trial of single agent avelumab …
cancer. Approximately 20% … , a single-arm phase 2 clinical trial of single agent avelumab …
Cabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers: a randomised, open-label, phase 1–2 trial
… We did a phase 1–2, open label, randomised study at two centres in … prostate cancer
clinicopathological criteria (AVPC-C), and used them to select patients for a single-group phase 2 …
clinicopathological criteria (AVPC-C), and used them to select patients for a single-group phase 2 …
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