… within coding regions, whereas the role of intergenic … intergenic mutations contribute to the
evolutionary response of a clinically important bacterial pathogen, Pseudomonas aeruginosa, …

… Our work revealed a high potential effect of intergenic variants on resistance evolution. In
particular, we found several cases in which the surviving populations had a single variant in …

… aeruginosa, indels in intergenic homopolymeric tracts promote adaptation both, to our … of
mutations in the intergenic regions for the adaptation of P. aeruginosa to the conditions of cystic …

… associated with persistence during infection and other stressful … by evolving Pseudomonas
aeruginosa populations in biofilm-… has implicated intergenic regulatory regions as critical in P. …

… Pseudomonas aeruginosa chronically infects the lungs of patients with cystic fibrosis (CF).
During infection the bacteria evolve … phenotypic approaches to compare multiple isolates of P. …

… 62.0 % GC for intergenic regions. The GC-content of full genomes was slightly lower than
the core genome (66.4 % GC for coding regions and 60.7 % GC for intergenic regions). The …

… involving intergenic regions, and transcriptomic and proteomic profiles of … The ability of
Pseudomonas aeruginosa to establish a chronic infection in … In fact, the high plasticity of the P. …

… to study the evolutionary dynamics of Pseudomonas aeruginosa in a mixed-strain infection.
We … Both sequences inserted at the intergenic region (−1549/+271) between PA14_33350 (…

… Here we use experimental evolution to follow changes in the production of a model public
… , of the bacterium Pseudomonas aeruginosa. After 1200 generations of evolution in nine …

… Using this 93 bp sequence (annotated as the intergenic region between PA1128 and PA1134,
Figure 2), we detected the same 36 exlBA positive strains that were detected using the 56 …