… bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 randomized clinical trial

TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
… revealed superior PFS with osimertinib compared with first-generation EGFR TKIs (erlotinib
or gefitinib), and osimertinib has become the preferred first-line therapy. Consequently, there …

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn… - Cancer Research and …, 2019 - synapse.koreamed.org
… Our purpose of this study is to investigate how afatinib is used in real-world practice, and
whether it leads to different clinical outcomes compared with gefitinib or erlotinib. …

… of erlotinib 100 mg/d vs. gefitinib 250 mg/d in EGFR-mutated advanced non-small cell lung cancer (E100VG250): an open-label, randomized, phase 2 study

S Zhao, Z Zhang, W Fang, Y Zhang, Z Zhang… - Frontiers in …, 2020 - frontiersin.org
randomized controlled trial to directly compare lower dose erlotinib with standard dose gefitinib
… Therefore, in Stage IV EGFR mutated NSCLC, this study showed that erlotinib 100 mg/d …

A phase II randomized trial of panitumumab, erlotinib, and gemcitabine versus erlotinib and gemcitabine in patients with untreated, metastatic pancreatic …

TR Halfdanarson, NR Foster, GP Kim, JP Meyers… - The …, 2019 - academic.oup.com
… now part of Alliance for Clinical Trials in Oncology) trial N064B compared gemcitabine plus
erlotinib versus gemcitabine plus combined EGFR inhibition with erlotinib and panitumumab. …

… versus erlotinib alone in patients with EGFR-positive advanced non-small-cell lung cancer: a systematic review and meta-analysis of randomised controlled trials

W Deng, K Wang, Y Jiang, D Li, C Bao, J Luo, L Liu… - BMJ open, 2022 - bmjopen.bmj.com
… (gefitinib and erlotinib) as a result of acquired drug resistance and relapse.7 Combination
treatments with EGFR TKIs is one strategy to overcome acquired resistance and to improve …

[HTML][HTML] A phase III, randomized, open-label study of ASP8273 versus erlotinib or gefitinib in patients with advanced stage IIIB/IV non-small-cell lung cancer

RJ Kelly, FA Shepherd, A Krivoshik, F Jie, L Horn - Annals of Oncology, 2019 - Elsevier
… The current study examines the efficacy, safety, and tolerability of ASP8273 versus
erlotinib or gefitinib in patients with non-small-cell lung cancer (NSCLC) with activating EGFR …

Phase III clinical trial for the combination of erlotinib plus ramucirumab compared with osimertinib in previously untreated advanced or recurrent non–small cell lung …

N Haratake, H Hayashi, M Shimokawa, Y Nakano… - Clinical lung cancer, 2022 - Elsevier
gefitinib or erlotinib in patients with the L858R. The RELAY … aware, our study is the first phase
III clinical trial to target only … the present study is achieved, the combination of erlotinib plus …

Combination of gefitinib and olaparib versus gefitinib alone in EGFR mutant non-small-cell lung cancer (NSCLC): A multicenter, randomized phase II study (GOAL)

R Garcia-Campelo, O Arrieta, B Massuti… - Lung Cancer, 2020 - Elsevier
… inhibitors (TKIs), erlotinib and gefitinib, the second-generation … EGFR TKIs are being
evaluated in multiple clinical trials. … erlotinib treated EGFR mutant patients [15,19]. In the present …

… Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A Randomized Phase II Study

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
… ) trial showed the superiority of adjuvant gefitinib over … open-label, phase II, randomized
controlled trial of erlotinib versus GC … All patients were randomly assigned 1:1 to receive erlotinib

Gefitinib Versus Gefitinib Plus Pemetrexed and Carboplatin Chemotherapy in EGFR-Mutated Lung Cancer

V Noronha, VM Patil, A Joshi, N Menon… - Journal of Clinical …, 2020 - ascopubs.org
Gefitinib, erlotinib, and afatinib have comparable efficacies in terms of objective response …
-generation oral TKIs for T790M mutation; clinical trials if MET amplification, PIK3CA, BRAF, or …