The effects of repeated morphine treatment on the endogenous cannabinoid system in the ventral tegmental area
… Coronal slices containing the VTA were sectioned at a … the production of endogenous 2-AG
on sustained morphine-induced … Our results showed that rats receiving sustained morphine …
on sustained morphine-induced … Our results showed that rats receiving sustained morphine …
Acute and chronic effects of morphine on Low-Mg2+ ACSF-induced epileptiform activity during infancy in mice hippocampal slices
… In each group morphine was applied to at least six brain slices. … The endogenous opioids
and icv morphine stimulate only a … in rats by subcutaneous implant of pellets of morphine over 8 …
and icv morphine stimulate only a … in rats by subcutaneous implant of pellets of morphine over 8 …
Dezocine alleviates morphine-induced dependence in rats
F Wu, H Babazada, H Gao, XP Huang, C Xi… - Anesthesia & …, 2019 - journals.lww.com
… The brain tissues were collected and fixed. Transverse brain sections were obtained and
processed as described previously for immunofluorescence assay. Sections were incubated in …
processed as described previously for immunofluorescence assay. Sections were incubated in …
… of dopamine D1-and D2-like receptors in the CA1 region of the hippocampus on expression and extinction of morphine-induced conditioned place preference in rats
… ; the brain was removed and cut coronally in 50-μm sections … 2B) experiments was verified
according to the rat brain atlas [… be inhibited by endogenous GABA [29] and morphine can …
according to the rat brain atlas [… be inhibited by endogenous GABA [29] and morphine can …
Dentate gyrus μ-opioid receptor-mediated neurogenic processes are associated with alterations in morphine self-administration
H Zhang, M Jia, XW Wang, C Ye, Y Li, N Wang… - Scientific reports, 2019 - nature.com
… as morphine and heroin) can mimic endogenous opioid peptides and interfere with the
homeostasis of the endogenous opioid … For rat brain slices, rats were anesthetized and perfused …
homeostasis of the endogenous opioid … For rat brain slices, rats were anesthetized and perfused …
Endogenous opioid peptides and brain development: Endomorphin‐1 and Nociceptin play a sex‐specific role in the control of oligodendrocyte maturation and brain …
E Mohamed, CE Paisley, LC Meyer, JW Bigbee… - Glia, 2020 - Wiley Online Library
… timing of myelination in the rat brain is disturbed by in utero … However, the functions of the
endogenous opioid receptor … staining of coronal brain sections with MBP antibody. Shown are …
endogenous opioid receptor … staining of coronal brain sections with MBP antibody. Shown are …
Simultaneous intrathecal injection of muscimol and endomorphin‐1 alleviates neuropathic pain in rat model of spinal cord injury
M Hosseini, Z Karami, M Yousefifard… - Brain and …, 2020 - Wiley Online Library
… Also, special attention has been focused on endogenous morphine (endomorphins) in
reducing chronic pain originates from damage to the nervous system. The purpose of this study is …
reducing chronic pain originates from damage to the nervous system. The purpose of this study is …
Transgenic increase in the β‐endorphin concentration in cerebrospinal fluid alleviates morphine‐primed relapse behavior through the μ opioid receptor in rats
Y He, Y Lu, Y Shen, F Wu, X Xu, E Kong… - Journal of Medical …, 2019 - Wiley Online Library
… -embedded rat brain tissue was cut into 4-μm-thick sections. … of the endogenous opioid
peptide in targeted brain regions via … specific brain regions and/or nuclei involved in this process. …
peptide in targeted brain regions via … specific brain regions and/or nuclei involved in this process. …
[HTML][HTML] The effect of morphine on rat microglial phagocytic activity: An in vitro study of brain region-, plating density-, sex-, morphine concentration-, and receptor …
DN King'uyu, L Nti-Kyemereh, JL Bonin… - Journal of …, 2023 - Elsevier
… M morphine increased phagocytosis in cortical … morphine in striatal microglia plated at 10
K density is mediated via TLR4, and not μORs. Overall, our data suggest that in rats, a morphine…
K density is mediated via TLR4, and not μORs. Overall, our data suggest that in rats, a morphine…
Different neuronal populations mediate inflammatory pain analgesia by exogenous and endogenous opioids
XY Zhang, YN Dou, L Yuan, Q Li, YJ Zhu, M Wang… - Elife, 2020 - elifesciences.org
… the analgesic effect of morphine in acute pain, but not in endogenous opioid analgesia during
… (b) Graphs showing the immunostaining of MOR in brain sections of Oprm1 KI/KI , Vglut2-…
… (b) Graphs showing the immunostaining of MOR in brain sections of Oprm1 KI/KI , Vglut2-…
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