… patients with NSCLC, and EGFR mutations are now listed among several mutations that
should be routinely screened in patients with lung cancer with an adenocarcinoma component […

… growth factor receptor (egfr) mutated non-small cell lung cancer (nsclc). (a) comparisons on
progression free survival and overall survival in patients with advanced egfr mutated nsclc. (b…

… of EGFR mutation. In this review, we first provide a discussion of EGFR-mutated lung cancer
and … setting against both common and rare EGFR mutations. Second, we discuss common …

… low frequency mutations, given the high prevalence of lung cancer overall, it is estimated
that over 30,000 NSCLC patient new diagnoses per year will harbour rare EGFR mutations. …

… is the most common subtype, represents the leading cause of cancer related-… mutation in
non-small-cell lung cancer. Alterations in Kirsten rat sarcoma, epidermal growth factor receptor, …

… About inclusion criteria, data relative to EGFR mutations in lung cancers were extracted from
the Catalogue of Somatic Mutations in Cancer (COSMIC) database, release version 90 (last …

… Lung cancer is the leading cause of cancer-related mortality worldwide [1], and is clinically
classified into small cell lung cancer (SCLC) and non-small cell lung cancer … % of lung cancer. …

… In China, it is also the most common cancer and leading cause of cancer-… receptor (EGFR)
mutations. NSCLC harboring EGFR mutations constitutes about 10–20% of all lung cancer …

… into on-target EGFR kinase mutations. We discuss array of mutations, their structural effects
on the … strategies to overcome the individual resistance profiles found in lung cancer patients. …

… Lung cancer is the leading cause of cancer-related mortality globally, … lung cancer (NSCLC)
is the most common type of lung cancer, accounting for approximately 80–90% of all lung …