… DAMPs recognized by CD44 and P2X7 are hyaluronan and … The function of peritoneal
macrophages in sterile injury is … However, peritoneal macrophages recruited to sterile liver injury …

… The initiation of a sterile intrinsic inflammatory event induces HA accumulation at … injury has
been proposed to involve recognition of components of damaged cells by pattern recognition …

… High molecular weight (HMW) hyaluronic acid (HA) has been studied in sterile injury models
… Instillation of hyaluronan reverses acid instillation injury to the mammalian blood gas barrier…

… as in alveolar macrophages from injured lungs [25,31,32]. On the other hand, a hyaluronan
tetrasaccharide blocks TLR2 activation and protects against ischemic brain injury [33]. The …

… space are modified by injuries, they can become … of sterile injury, recognized by CD44
receptor and others [4,5]. Moreover, failure to remove HA degradative products from sites of injury …

… hyaluronan (HA) and the Receptor for Hyaluronan-Mediated Motility (RHAMM, CD168) have
been implicated in the response to acute lung injury… to injured WT animals, injured RHAMM …

… , or hyaluronan (HA), is a nonsulfated glucosaminoglycan that has long been recognized for
… species generated during inflammation or tissue injury. Importantly, hyaluronidases consist …

… the plasma hyaluronan concentration were higher in all groups compared with baseline
values. Sterile injury such as surgical instrumentation alone can alter hyaluronan production …

… are first recognized by the host pattern recognition receptors (… Defects in pathogen recognition
by PRRs and subsequent … induced by the pathogen recognition and signaling cascades …

… responsible for hyaluronan catabolism in mice. Cemip −/− mice failed to digest hyaluronan
and had … Stabilization of large-molecular-weight hyaluronan enabled increased expression of …