[HTML][HTML] Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway

S Liu, J Pi, Q Zhang - Redox biology, 2022 - Elsevier
… involves several key signaling components and regulatory events. Here, the … antioxidant
response elements (ARE) in the promoters of a battery of target genes including antioxidant

Role of selenoproteins in redox regulation of signaling and the antioxidant system: a review

Y Zhang, YJ Roh, SJ Han, I Park, HM Lee, YS Ok… - Antioxidants, 2020 - mdpi.com
… Humans have 25 selenoproteins, most of which are functionally characterized as
oxidoreductases, where the Sec residue plays a catalytic role in redox regulation and antioxidant

Unification of opposites between two antioxidant transcription factors Nrf1 and Nrf2 in mediating distinct cellular responses to the endoplasmic reticulum stressor …

Y Zhu, Z Zheng, S Hu, X Ru, Z Fan, L Qiu, Y Zhang - Antioxidants, 2019 - mdpi.com
… a master regulator of antioxidant responses to cellular stress, … , transactivation of ARE (antioxidant
response element)-driven … regulate transcription of antioxidant/electrophile response

Antioxidant and adaptative response mediated by Nrf2 during physical exercise

N Vargas-Mendoza, Á Morales-González… - Antioxidants, 2019 - mdpi.com
… sequence known as the antioxidant response element (ARE, 5′-… with the antioxidant and
detoxifying response, such as the … SFN regulation and that the antioxidant response can play …

ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress

C Sarcinelli, H Dragic, M Piecyk, V Barbet, C Duret… - Cancers, 2020 - mdpi.com
… the master regulator of the cellular antioxidant response nuclear factor erythroid 2-related …
Indeed, we identified a putative C/EBP-ATF Response Element (CARE) in the human NRF2 …

Isoflavone biochanin A, a novel nuclear factor erythroid 2‐related factor 2 (Nrf2)‐antioxidant response element activator, protects against oxidative damage in HepG2 …

F Liang, W Cao, Y Huang, Y Fang, Y Cheng, S Pan… - Biofactors, 2019 - Wiley Online Library
… In this study, the effects of isoflavones on the nuclear factor E2‐related factor 2 (Nrf2)–antioxidant
response element (ARE) signaling pathway and the underlying molecular mechanisms …

NRF2, a transcription factor for stress response and beyond

F He, X Ru, T Wen - International journal of molecular sciences, 2020 - mdpi.com
regulatory network and establishes NRF2 as a truly pleiotropic transcription factor. Here we
summarize the complex regulatory … to recognize antioxidant response elements (ARE) for …

Redox regulation of the immune response

G Morris, M Gevezova, V Sarafian… - Cellular & Molecular …, 2022 - nature.com
The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine: (a) the role of redox-sensitive transcription …

In vivo and in vitro evidence for the involvement of Nrf2-antioxidant response element signaling pathway in the inflammation and oxidative stress induced by …

M Radan, M Dianat, M Badavi, SA Mard… - Free radical …, 2019 - Taylor & Francis
Full article: In vivo and in vitro evidence for the involvement of Nrf2-antioxidant response
element signaling pathway in the inflammation and oxidative stress induced by particulate …

The role of the antioxidant response in mitochondrial dysfunction in degenerative diseases: Cross‐talk between antioxidant defense, autophagy, and apoptosis

MLH Huang, S Chiang, DS Kalinowski… - Oxidative Medicine …, 2019 - Wiley Online Library
… signaling functions, with their levels being regulated by a suite of cellular antioxidants [2]. …
binding to its target DNA sequence known as the antioxidant response element (ARE) [15, 16]. …