The regulatory T cell in active systemic lupus erythematosus patients: a systemic review and meta-analysis

W Li, C Deng, H Yang, G Wang - Frontiers in immunology, 2019 - frontiersin.org
… ,” combined with “systemic lupus erythematosus.” Reviews were excluded and only articles
lupus erythematosus exhibits a dynamic and continuum spectrum of effector/regulatory T cells

[HTML][HTML] New insights in systemic lupus erythematosus: from regulatory T cells to CAR-T-cell strategies

M Doglio, T Alexander, N Del Papa… - Journal of Allergy and …, 2022 - Elsevier
… less toxicity than autologous hematopoietic stem cell transplantation. An emerging field is to
… of regulatory T cells, which are dysfunctional in patients with systemic lupus erythematous, …

Regulatory T-cell levels in systemic lupus erythematosus patients: a meta-analysis

Y Zhu, Y Huang, B Ming, X Wu, Y Chen, L Dong - Lupus, 2019 - journals.sagepub.com
… searched using ‘systemic lupus erythematosus’ and ‘regulatory T-cells’ as relevant key …
among peripheral blood mononuclear cells (PBMCs) and CD4 + T-cells was performed using …

Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis

…, E Lazaro, L Couzi, P Duffau, T Barnetche… - Science Translational …, 2021 - science.org
… P-selectin as a treatment for lupus Dysfunctional regulatory T (T reg ) cells are known to be
… pathogenesis of systemic lupus erythematosus (SLE), but the mechanisms mediating T reg …

[HTML][HTML] Selective expansion of regulatory T cells by NKTR-358 in healthy volunteers and patients with systemic lupus erythematosus

C Fanton, R Furie, V Chindalore, R Levin, I Diab… - Journal of Translational …, 2022 - Elsevier
… Systemic lupus erythematosus (SLE) is an autoimmune disease with multi-organ …
Impaired interleukin-2 (IL-2) production and dysfunction of regulatory T cells (Tregs) have been …

Regulatory T cells and their association with serum markers and symptoms in systemic lupus erythematosus and rheumatoid arthritis

V Kailashiya, U Singh, R Rana, NK Singh… - Immunological …, 2019 - Taylor & Francis
… Purpose: Impairment in number and functions of regulatory T cells (Treg) has been found
to be associated with many autoimmune diseases including systemic lupus erythematosus (…

Imbalance between Th17 and regulatory T cells in patients with systemic lupus erythematosus combined EBV/CMV viraemia.

R Su, Z Li, Y Wang, Y Liu, X Zheng, C Gao… - Clinical and …, 2019 - europepmc.org
… between T helper 17 (Th17) cells and regulatory T (Treg) cells … subsets, especially CD4+
T cells, in patients with SLE … The absolute numbers of lymphocytes and CD4+ T cells in …

MicroRNA-125a-loaded polymeric nanoparticles alleviate systemic lupus erythematosus by restoring effector/regulatory T cells balance

J Zhang, C Chen, H Fu, J Yu, Y Sun, H Huang… - ACS …, 2020 - ACS Publications
cells (TCR-β + CD44 lo CD62L hi ) (Figure 2C,D). Since cellular … T cells, we speculated
that activated T cells might have a stronger uptake capacity. To validate our hypothesis, T cells

T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy

A Sharabi, GC Tsokos - Nature Reviews Rheumatology, 2020 - nature.com
… pathogenic effector T cell activation and differentiation and the promotion of regulatory T cells.
… The metabolic pathways in memory T cells and regulatory T (T reg ) cells are different from …

Mouse IL-2/CD25 fusion protein induces regulatory T cell expansion and immune suppression in preclinical models of systemic lupus erythematosus

JH Xie, Y Zhang, M Loubeau, P Mangan… - The Journal of …, 2021 - journals.aai.org
… Systemic lupus erythematosus (SLE) is associated with an IL-2–deficient state, with regulatory
T cells (Tregs) showing diminished immune regulatory capacity. A low dose of IL-2 has …