During determination of chloroquine (CQ) and its main metabolite desethylchloroquine
(CQM) in blood samples applied to filter paper, we observed contamination of the paper by …

Two new methods for the simultaneous determination of chloroquine and its two main
metabolites (monodesethylchloroquine and bisdesethylchloroquine) in biological samples …

Background Hydroxychloroquine (HCQ) and azithromycin (AZM) are antimalarial drugs
recently reported to be active against severe acute respiratory syndrome coronavirus-2 …

BACKGROUND: Hydroxychloroquine is routinely used in managing systemic lupus
erythematosus and rheumatoid arthritis. Whole blood levels are currently measured in the …

Introduction Hydroxychloroquine was recently promoted in patients infected with COVID-19
infection. A recent experimental study has suggested an increased toxicity of …

MATERIALS AND METHODS Urinary creatinine was estimated by the alkaline picrate
method described by Owen, Iggo, Scandrett and Stewart (1954) and Ralston (1955) …

Abstract Background In Central and South America and Eastern and Southern Africa,
Plasmodium vivax infections accounts for 71-81% and 5% of malaria cases, respectively. In …

Quinine and chloroquine poisoning are characterized by severe cardiovascular toxicity
resulting from sodium and potassium channel blockade, leading to hypotension, shock …

A spectrophotofluorometric method for determination of chloroquine in body fluids was
compared with a recently developed high performance liquid chromatographic (HPLC) …

Liquid‐phase microextraction based on polypropylene hollow fibers and CE were applied
for the chiral determination of hydroxychloroquine (HCQ) and its metabolites …