The dental abnormalities are the typical features of many ectodermal dysplasias along with
congenital malformations of nails, skin, hair, and sweat glands. However, several reports of …

Dental agenesis is one of the most common congenital craniofacial abnormalities. Dental
agenesis can be classified, relative to the number of missing teeth (excluding third molars) …

Background Dental agenesis is the most common, often heritable, developmental anomaly
in humans. Although WNT10A gene mutations are known to cause rare syndromes …

Mutations in WNT10A have frequently been reported as etiologic for tooth agenesis (TA).
However, the effects of WNT10A variation on gene/protein function and contribution to TA …

The goal of this study was to identify the pathogenic gene variants in patients with odonto-
onycho-dermal dysplasia syndrome (OODD) or nonsyndromic tooth agenesis. Four …

Background Oligodontia is a severe form of tooth agenesis characterized by the absence of
six or more permanent teeth. Oligodontia has complex etiology and variations in numerous …

Both X-linked hypohidrotic ectodermal dysplasia (XLHED) and non-syndromic tooth
agenesis (NSTA) result in symptoms of congenital tooth loss. This study investigated genetic …

Tooth agenesis is one of the most common orodental anomalies that demonstrate
phenotypic and genotypic heterogeneity with a prevalence of 2.5%–7%. Mutations in …

Tooth agenesis (TA) is one of the most common developmental anomalies that affects the
number of teeth. An extensive analysis of publicly accessible databases revealed 15 …

Objectives To identify potentially pathogenic mutations for tooth agenesis by whole‐exome
sequencing. Subjects and Methods Ten Chinese families including five families with …