Highlights•Molecular mechanisms of HTLV-1 oncogenesis.•Innate and acquired immune
response to HTLV-1.•Clonality of HTLV-1 in vivo.•We bring together the host and viral factors …

Human T-cell leukemia virus type I (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL)
in 5% of infected people with a decades-long latency. Charles RM Bangham reviews the …

Human T-cell lymphoma virus (HTLV)-1 was the first human retrovirus to be discovered. It
has been recognized as the cause of adult T-cell leukemia (ATL). In addition to giving a …

Adult T-cell leukaemia (ATL) is caused by the human T-cell lymphotropic virus type 1 (HTLV-
1). HTLV-1 has elaborated strategies to persist and replicate in the presence of a strong …

Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) was the first oncogenic human
retrovirus to be discovered, more than 25 years ago. HTLV-1 infects 15 to 20 million …

The human T-lymphotropic virus type 1 (HTLV-1) retrovirus infects 10–20 million people
globally, with endemic regions in southwestern Japan, the Caribbean basin, Africa, and …

Human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 are related but pathogenically
distinct viruses. HTLV-1 mainly causes adult T cell leukemia, while HTLV-2 is not associated …

Human T lymphotropic virus type 1 (HTLV-1) causes a range of chronic inflammatory
diseases and an aggressive malignancy of T lymphocytes known as adult T-cell …

Human T-cell leukemia virus type 1 (HTLV-1) is a complex human delta retrovirus that
infects an estimated 10–20 million people worldwide (Gessain and Cassar 2012). HTLV-1 …

There are two families of viruses that contribute to lymphomagenesis in humans:
herpesviruses and retroviruses. The two herpesviruses are the Epstein-Barr virus (EBV) and …