[HTML][HTML] Characterization of Naturally Acquired Immunity to a Panel of Antigens Expressed in Mature P. falciparum Gametocytes
MK Muthui, E Takashima, BR Omondi… - Frontiers in cellular …, 2021 - frontiersin.org
Introduction Naturally acquired immune responses against antigens expressed on the
surface of mature gametocytes develop in individuals living in malaria-endemic areas …
surface of mature gametocytes develop in individuals living in malaria-endemic areas …
Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria
Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce
malaria transmission and are thus attractive targets for malaria control. However, very little is …
malaria transmission and are thus attractive targets for malaria control. However, very little is …
Plasmodium falciparum gametocyte-specific antibody profiling reveals boosting through natural infection and identifies potential markers of gametocyte exposure
Malaria elimination efforts would benefit from vaccines that block transmission of
Plasmodium falciparum gametocytes from humans to mosquitoes. A clear understanding of …
Plasmodium falciparum gametocytes from humans to mosquitoes. A clear understanding of …
The acquisition of humoral immune responses targeting Plasmodium falciparum sexual stages in controlled human malaria infections
RM de Jong, M Alkema, T Oulton, E Dumont… - Frontiers in …, 2022 - frontiersin.org
Individuals infected with P. falciparum develop antibody responses to intra-erythrocytic
gametocyte proteins and exported gametocyte proteins present on the surface of infected …
gametocyte proteins and exported gametocyte proteins present on the surface of infected …
Naturally acquired immunity to sexual stage P. falciparum parasites
WJR Stone, KW Dantzler, SK Nilsson, CJ Drakeley… - Parasitology, 2016 - cambridge.org
Gametocytes are the specialized form of Plasmodium parasites that are responsible for
human-to-mosquito transmission of malaria. Transmission of gametocytes is highly effective …
human-to-mosquito transmission of malaria. Transmission of gametocytes is highly effective …
Persistent Plasmodium falciparum infections enhance transmission-reducing immunity development
Subclinical infections that serve as reservoir populations to drive transmission remain a
hurdle to malaria control. Data on infection dynamics in a geographical area is required to …
hurdle to malaria control. Data on infection dynamics in a geographical area is required to …
Immune Responses to Gametocyte Antigens in a Malaria Endemic Population—The African falciparum Context: A Systematic Review and Meta-Analysis
Background: Malaria elimination remains a priority research agenda with the need for
interventions that reduce and/or block malaria transmission from humans to mosquitoes …
interventions that reduce and/or block malaria transmission from humans to mosquitoes …
Naturally acquired immunity against immature Plasmodium falciparum gametocytes
The recent decline in global malaria burden has stimulated efforts toward Plasmodium
falciparum elimination. Understanding the biology of malaria transmission stages may …
falciparum elimination. Understanding the biology of malaria transmission stages may …
A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals
Background Antibodies play a central role in naturally acquired immunity against
Plasmodium falciparum. Current assays to detect anti-plasmodial antibodies against native …
Plasmodium falciparum. Current assays to detect anti-plasmodial antibodies against native …
The Dynamics of Naturally Acquired Immune Responses to Plasmodium falciparum Sexual Stage Antigens Pfs230 & Pfs48/45 in a Low Endemic Area in Tanzania
T Bousema, W Roeffen, H Meijerink, H Mwerinde… - PloS one, 2010 - journals.plos.org
Background Naturally acquired immune responses against sexual stages of P. falciparum
can reduce the transmission of malaria from humans to mosquitoes. These antigens are …
can reduce the transmission of malaria from humans to mosquitoes. These antigens are …