Lipid structural diversity strongly affects biomembrane chemico-physical and structural
properties in addition to membrane-associated events. At high concentrations, cholesterol …

The distribution of cholesterol in asymmetric lipid bilayers was studied by extensive coarse-
grained molecular dynamics simulations. The effects of the lipid head group charge, acyl …

Elevated free cholesterol levels lead to atherosclerotic-like changes in membrane structure,
including cholesterol crystalline domain formation. Omega-3 fatty acids such as …

Lateral heterogeneity of a cell membrane, including the formation of lipid raft-like clusters
and the inter-leaflet coupling of specific phase domains, is crucial for cellular functions such …

Drug molecules either bind to membrane-bound targets or permeate through cell
membranes to reach intracellular targets, and hence, their membrane partition and …

Lipid membranes can spontaneously organize their components into domains of different
sizes and properties. The organization of membrane lipids into nanodomains might …

Cholesterol is the most interesting and the most studied membrane molecule. The
knowledge of its fundamental interaction with other molecules can help us to understand the …

Based on indirect observations, there currently exists a consensus that the plasma
membrane of mammalian cells exhibits nontrivial lateral heterogeneities in the form of …

The architecture of a biological membrane hinges upon the fundamental fact that its
properties are determined by more than the sum of its individual components. Studies on …

Cholesterol plays a vital role in determining the physiochemical properties of cell
membranes. However, the detailed nature of cholesterol–lipid interactions is a subject of …