Electrospun nanofiber nerve guidance conduits for peripheral nerve regeneration: A review

S Lee, M Patel, R Patel - European Polymer Journal, 2022 - Elsevier
Peripheral nerve injuries (PNIs) often lead to permanent impairment of functional movement
and sensory loss due to limited effective treatment options. Currently, autologous nerve …

[HTML][HTML] Nanofibrous nerve guidance conduits decorated with decellularized matrix hydrogel facilitate peripheral nerve injury repair

C Zheng, Z Yang, S Chen, F Zhang, Z Rao, C Zhao… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Peripheral nerve injury (PNI) is a great challenge for regenerative medicine.
Nerve autograft is the gold standard for clinical PNI repair. Due to its significant drawbacks …

Use of electrospinning to construct biomaterials for peripheral nerve regeneration

Q Quan, B Chang, HY Meng, RX Liu… - Reviews in the …, 2016 - degruyter.com
A number of limitations associated with the use of hollow nerve guidance conduits (NGCs)
require further discussion. Most importantly, the functional recovery outcomes after the …

Progress of electrospun fibers as nerve conduits for neural tissue repair

Y Mu, F Wu, Y Lu, L Wei, W Yuan - Nanomedicine, 2014 - Future Medicine
Nerve tissue regeneration approaches have gained much attention in recent years, and
nerve conduits (NCs), which facilitate nerve tissue regeneration, have become an attractive …

Nanoparticles for neurotrophic factor delivery in nerve guidance conduits for peripheral nerve repair

A Escobar, RL Reis, JM Oliveira - Nanomedicine, 2022 - Future Medicine
Peripheral nerve injuries are a major source of disabilities, and treatment of long nerve gap
autografts is the gold standard. However, due to poor availability and donor-site morbidity …

Advances in electrospun nerve guidance conduits for engineering neural regeneration

S Behtaj, JAK Ekberg, JA St John - Pharmaceutics, 2022 - mdpi.com
Injuries to the peripheral nervous system result in devastating consequences with loss of
motor and sensory function and lifelong impairments. Current treatments have largely relied …

Advances in biomimetic nerve guidance conduits for peripheral nerve regeneration

F Mankavi, R Ibrahim, H Wang - Nanomaterials, 2023 - mdpi.com
Injuries to the peripheral nervous system are a common clinical issue, causing dysfunctions
of the motor and sensory systems. Surgical interventions such as nerve autografting are …

Chitosan-based nerve guidance conduit with microchannels and nanofibers promotes schwann cells migration and neurite growth

G Zhou, Y Chen, F Dai, X Yu - Colloids and Surfaces B: Biointerfaces, 2023 - Elsevier
Peripheral nerve injury (PNI) is the leading cause of permanent dysfunction in movement
and sensation. Despite the rapid development of tissue engineering in peripheral nerve …

[HTML][HTML] Polymeric guide conduits for peripheral nerve tissue engineering

H Jiang, Y Qian, C Fan, Y Ouyang - Frontiers in bioengineering and …, 2020 - frontiersin.org
Peripheral nerve injuries (PNIs) are usually caused by trauma, immune diseases, and
genetic factors. Peripheral nerve injury (PNI) may lead to limb numbness, muscle atrophy …

Novel spiral structured nerve guidance conduits with multichannels and inner longitudinally aligned nanofibers for peripheral nerve regeneration

MB Shah, W Chang, G Zhou, JS Glavy… - … Research Part B …, 2019 - Wiley Online Library
Nerve guidance conduits (NGCs) are artificial substitutes for autografts, which serve as the
gold standard in treating peripheral nerve injury. A recurring challenge in tissue engineered …