BACKGROUND Coronary atherosclerosis is a chronic inflammatory disease which
progresses to luminal stenosis and plaque rupture events. Recent developments in non …

Background: Coronary 18F-fluoride positron emission tomography identifies ruptured and
high-risk atherosclerotic plaque. The optimal method to identify, to quantify, and to …

Objectives: With combined positron emission tomography and computed tomography (CT),
we investigated coronary arterial uptake of 18F-sodium fluoride (18F-NaF) and 18F …

Purpose In the last years, the identification of vulnerable atherosclerotic plaques to prevent
acute coronary events has been one of the main objectives of the cardiovascular science …

The emphasis of current cardiovascular imaging modalities is on the anatomic detection of
coronary artery luminal narrowing. However, in the clinical setting, vulnerable plaques that …

Atherothrombotic events in coronary arteries are most often due to rupture of unstable
plaque resulting in myocardial infarction. Radiolabeled molecular imaging tracers directed …

Myocardial infarction remains the commonest cause of premature death worldwide with
coronary atherosclerotic plaque rupture often initiating the event. Despite an ever-expanding …

A significant majority of atherosclerotic plaque ruptures occur in coronary arteries exhibiting
none or only modest luminal narrowing on coronary angiography. Emerging data suggest …

Recent advances in nuclear plaque imaging aim to achieve noninvasive identification of
vulnerable atherosclerotic plaques using positron emission tomography (PET) with 18 F …

Background Microcalcification is a key feature of vulnerable plaque. 18F-fluoride is a highly
sensitive positron emission tomography tracer that binds to microcalcification and combined …