[HTML][HTML] Changes in liver mechanical properties and water diffusivity during normal pregnancy are driven by cellular hypertrophy

K Garczyńska, H Tzschätzsch, AA Kühl… - Frontiers in …, 2020 - frontiersin.org
During pregnancy, the body's hyperestrogenic state alters hepatic metabolism and
synthesis. While biochemical changes related to liver function during normal pregnancy are …

Pregnancy and weaning regulate human maternal liver size and function

A Q. Bartlett, KK Vesco, JQ Purnell… - Proceedings of the …, 2021 - National Acad Sciences
During pregnancy, the rodent liver undergoes hepatocyte proliferation and increases in size,
followed by weaning-induced involution via hepatocyte cell death and stromal remodeling …

The influence of static portal pressure on liver biophysical properties

Y Safraou, K Krehl, T Meyer, S Mehrgan, JEL Jordan… - Acta Biomaterialia, 2023 - Elsevier
The liver is a highly vascularized organ where fluid properties, including vascular pressure,
vessel integrity and fluid viscosity, play a critical role in gross mechanical properties. To …

Transcriptome-wide analysis suggests that temporal changes in the relative contributions of hyperplasia, hypertrophy and apoptosis underlie liver growth in pregnant …

LR Price, KA Lillycrop, NA Irvine… - Biology of …, 2017 - academic.oup.com
Maternal liver undergoes structural and metabolic changes during pregnancy to meet the
demands of the developing fetus. In rodents, this involves increased liver weight, but the …

[HTML][HTML] Effect of Post-mortem Interval and Perfusion on the Biophysical Properties of ex vivo Liver Tissue Investigated Longitudinally by MRE and DWI

K Garczyńska, H Tzschätzsch, S Assili, AA Kühl… - Frontiers in …, 2021 - frontiersin.org
Structural changes of soft tissues on the cellular level can be characterized by
histopathology, but not longitudinally in the same tissue. Alterations of cellular structures and …

[HTML][HTML] On the relationship between metabolic capacities and in vivo viscoelastic properties of the liver

M Shahryari, S Keller, D Meierhofer… - … in Bioengineering and …, 2023 - frontiersin.org
The liver is the central metabolic organ. It constantly adapts its metabolic capacity to current
physiological requirements. However, the relationship between tissue structure and hepatic …

Maternal hepatic growth response to pregnancy in the mouse

G Dai, JJ Bustamante, Y Zou… - Experimental …, 2011 - journals.sagepub.com
Pregnancy is characterized by physiological adjustments in the maternal compartment. In
this investigation, the influence of pregnancy on maternal liver was examined in CD-1 mice …

Transient elastography and controlled attenuation parameter to evaluate hepatic steatosis and liver stiffness in postpartum patients

FN Hussain, E Rosenbluth, KM Feldman… - The Journal of …, 2023 - Taylor & Francis
Introduction Nonalcoholic fatty liver disease (NAFLD) affects 30% of adults in the United
States. Transient elastography (TE)(Fibroscan, Echosens, Paris, France) with controlled …

[HTML][HTML] Liver stiffness reversibly increases during pregnancy and independently predicts preeclampsia

FJ Ammon, A Kohlhaas, O Elshaarawy… - World journal of …, 2018 - ncbi.nlm.nih.gov
METHODS In this observational, diagnostic study, 537 pregnant women were prospectively
enrolled at the Department of Obstetrics and Gynecology, University hospital Heidelberg …

Sensitivity of multifrequency magnetic resonance elastography and diffusion-weighted imaging to cellular and stromal integrity of liver tissue

AA de Schellenberger, H Tzschätzsch… - Journal of …, 2019 - Elsevier
Microscopic structural alterations of liver tissue induced by freeze-thaw cycles give rise to
palpable property changes. However, the underlying damage to tissue architecture is …