Impaired microvascular circulation in distant organs following renal ischemia

JH Dominguez, D Xie, KJ Kelly - PLoS One, 2023 - journals.plos.org
Mortality in acute kidney injury (AKI) patients remains very high, although very important
advances in understanding the pathophysiology and in diagnosis and supportive care have …

Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury

M Horbelt, SY Lee, HE Mang… - American Journal …, 2007 - journals.physiology.org
Functional and structural abnormalities in the renal microvasculature are important
processes contributing to the pathophysiology of ischemic acute kidney injury (AKI). In this …

[HTML][HTML] Microvascular endothelial injury and dysfunction during ischemic acute renal failure

TA Sutton, CJ Fisher, BA Molitoris - Kidney international, 2002 - Elsevier
Microvascular endothelial injury and dysfunction during ischemic acute renal failure. The
pathophysiology of ischemic acute renal failure (ARF) appears to involve a complex …

The central role of renal microcirculatory dysfunction in the pathogenesis of acute kidney injury

C Ince - Nephron Clinical Practice, 2014 - karger.com
Acute kidney injury (AKI) is a rapidly developing condition often associated with critical
illness, with a high degree of morbidity and mortality, whose pathophysiology is ill …

The microcirculation of the septic kidney

L Zafrani, D Payen, E Azoulay, C Ince - Seminars in nephrology, 2015 - Elsevier
The renal microcirculation plays a major role in the delivery of blood and oxygen to the
kidney. In sepsis, alterations in renal microvascular perfusion, in conjunction with increased …

[HTML][HTML] High-resolution renal perfusion mapping using contrast-enhanced ultrasonography in ischemia-reperfusion injury monitors changes in renal microperfusion

K Fischer, FC Meral, Y Zhang, MG Vangel, FA Jolesz… - Kidney international, 2016 - Elsevier
Alterations in renal microperfusion play an important role in the development of acute kidney
injury with long-term consequences. Here we used contrast-enhanced ultrasonography as a …

Postischemic microvasculopathy and endothelial progenitor cell-based therapy in ischemic AKI: update and perspectives

D Patschan, A Kribben… - American Journal of …, 2016 - journals.physiology.org
Acute kidney injury (AKI) dramatically increases mortality of hospitalized patients. Incidences
have been increased in recent years. The most frequent cause is transient renal …

Acute ischemic injury to the renal microvasculature in human kidney transplantation

MG Snoeijs, H Vink, N Voesten… - American Journal …, 2010 - journals.physiology.org
Increased understanding of the pathophysiology of ischemic acute kidney injury in renal
transplantation may lead to novel therapies that improve early graft function. Therefore, we …

The macro-and microcirculation of the kidney

P Guerci, B Ergin, C Ince - Best Practice & Research Clinical …, 2017 - Elsevier
Acute kidney injury (AKI) remains one of the main causes of morbidity and mortality in the
intensive care medicine today. Its pathophysiology and progress to chronic kidney disease …

In vivo imaging of renal microvasculature in a murine ischemia–reperfusion injury model using optical coherence tomography angiography

BK Lee, W Kang, SH Oh, S Cho, I Shin, EJ Oh… - Scientific Reports, 2023 - nature.com
Optical coherence tomography angiography (OCTA) provides three-dimensional structural
and semiquantitative imaging of microvasculature in vivo. We developed an OCTA imaging …