Aims Zoledronic acid (ZA), a FDA approved drug has used widely in the treatment of bone
metastasis complications, has been linked to renal toxicity with unclear mechanism. The …

Zoledronic acid, a nitrogen‐containing bisphosphonate drug, is used for the treatment of
osteoporosis, Paget's disease of bone, and tumor‐induced osteolysis. Zoledronic acid has …

Zoledronic acid (ZLD) is a bisphosphonate drug widely administered against pathological
conditions such as hypercalcemia of malignancy, osteoporosis, bone metastases from solid …

The molecular mechanisms responsible for the cellular effects of the nitrogen-containing
bisphosphonate zoledronic acid (Zol) were assessed on several osteosarcoma cell lines …

Objective. To study and characterize the potential antitumoral effects of zoledronic acid (ZA)
on renal cancer cell lines in vitro. Material and methods. Three different and well …

Zoledronate (ZOL) is a third-generation bisphosphonate (BP), clinically used to treat lytic
bone lesions caused by malignancies or bone resorption disorders. Mechanistically, ZOL …

We investigated the apoptosis-inducing effect of zoledronic acid in human nasopharyngeal
carcinoma cell HNE-1 and explore the potential mechanism. Human nasopharyngeal …

Zoledronic acid (ZA), a bisphosphonate used to prevent skeletal fractures in patients with
cancers, was demonstrated to induce apoptosis in a number of cancer cells. Our previous …

Unlike low tumorigenic bulk tumor cells (non-CSCs), cancer stem cells (CSCs) are a subset
of tumor cells that can self-renew and differentiate into different cancer subtypes. CSCs are …

The wide uses of zinc oxide nanoparticles (nano-ZnO) in industrial, cosmetics, medicine,
food production and electronics associate with increase in occupational and public …