Protein phosphatase 2A (PP2A), in its activated form as a phosphatase, is a tumour
suppressor. However, when PP2A is phosphorylated at the tyrosine residue (pY307), it loses …

Abstract Purpose Protein phosphatase 2A (PP2A) is a family of serine/threonine
phosphatases that regulate multiple cellular signalling pathways involved in proliferation …

The protein phosphatase 2 (PP2A) holoenzyme consists of a catalytic subunit, a scaffold
subunit, and a regulatory subunit. Based on loss-of-function analysis using PP2A catalytic …

Breast cancer has become the most prevalent malignancy worldwide; however, therapeutic
efficacy is far from satisfactory. To alleviate the burden of this disease, it is imperative to …

Protein phosphatase 2A (PP2A) acts as a growth suppresser and is negatively influenced by
oncogenic signals. We determined its activity in various human breast carcinoma (HBC) cell …

Although evidence has suggested that the serine/threonine protein phosphatase 2A (PP2A)
might be a tumor suppressor protein, it has been difficult to pin down its role in tumor …

Protein Phosphatase 2A (PP2A) is an important and ubiquitously expressed serine
threonine phosphatase and regulates the function by dephosphorylating many critical …

Protein Phosphatase 2A (PP2A) is a major serine/threonine phosphatase in cells. It consists
of a catalytic subunit (C), a structural subunit (A), and a regulatory/variable B-type subunit …

Triple-negative breast cancer (TNBC) has the worst prognosis of all breast cancers, and
women diagnosed with TNBC currently lack targeted treatment options. To identify novel …

Protein serine/threonine phosphatases are important cellular signaling molecules and play
major roles in regulating many different functions including cell proliferation, senescence …