Adrenoceptors in GtoPdb v.2021.3 Page 1 IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F4/2021.3
Adrenoceptors in GtoPdb v.2021.3 Katrin Altosaar1, Poornima Balaji2, Richard A. Bond3 …

Adrenoceptors in GtoPdb v.2023.1 Page 1 IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F4/2023.1
Adrenoceptors in GtoPdb v.2023.1 Jillian G. Baker1, Poornima Balaji2, Richard A. Bond3 …

Adrenoceptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Page 1
IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F4/2019.4 …

Adrenoceptors have played a crucial role in the history of pharmacology. They were
essential parts of the work that led to the Nobel Prize in Physiology or Medicine to Sir James …

The subclassification of α-and β-adrenoceptors has resulted in many opportunities for drug
discovery. Important adrenoceptor targets include β2-agonists as bronchodilators, β1 or …

Compounds interacting with the a-adrenoceptors, such as phenethylamines, imidazolines,
and ergot alkaloids, have been used as therapeutic agents for decades. However, many of …

As β3‐adrenoceptors were first demonstrated to be expressed in adipose tissue they have
received much attention for their metabolic effects in obesity and diabetes. After the …

The cloning of multiple subtypes of both a1-and a2-adrenoceptors has renewed interest in
the therapeutic application of agents interacting with these receptors. Effort has primarily …

* Molecular Pharmacology Group, Departments of Biochemistry and Pharmacology,
University of Glasgow, Glasgow G12 SQQ, Scotland, UK; $ Institute of Physiology, Czech …

Historical setting In the latter part of the 1970s and the early 1980s three pharmaceutical
companies were attempting to design drugs that would retain the thermogenic and …