Breast conserving therapy after neoadjuvant chemotherapy; data from the Dutch Breast Cancer Audit

PER Spronk, JH Volders, P van den Tol… - European Journal of …, 2019 - Elsevier
Introduction NAC has led to an increase in breast conserving surgery (BCS) worldwide. This
study aims to analyse trends in the use of neoadjuvant chemotherapy (NAC) and the impact …

Disease-free and overall survival after neoadjuvant chemotherapy in breast cancer: breast-conserving surgery compared to mastectomy in a large single-centre cohort …

JM Simons, JG Jacobs, JP Roijers, MA Beek… - Breast Cancer Research …, 2021 - Springer
Purpose The extended role of breast-conserving surgery (BCS) in the neoadjuvant setting
may raise concerns on the oncologic safety of BCS compared to mastectomy. This study …

Neoadjuvant chemotherapy in breast-conserving surgery–Consequences on margin status and excision volumes: a nationwide pathology study

JH Volders, MH Haloua, NMA Krekel… - European Journal of …, 2016 - Elsevier
Background Neoadjuvant chemotherapy (NACT) is increasingly used in patients with
operable disease due to the potential of converting patients requiring mastectomy to breast …

Breast-conserving surgery following neoadjuvant therapy-a systematic review on surgical outcomes

JH Volders, VL Negenborn, PE Spronk… - Breast cancer research …, 2018 - Springer
Purpose Neoadjuvant chemotherapy (NACT) is increasingly used in breast cancer
treatment. One of the main goals of NACT is to reduce the extent of local surgery of the …

Evaluating the effect of neoadjuvant chemotherapy on surgical outcomes after breast conserving surgery

MR Woeste, N Bhutiani, M Donaldson… - Journal of Surgical …, 2021 - Wiley Online Library
Background Neoadjuvant chemotherapy (NAC) increases breast‐conserving surgery (BCS)
rates with comparable locoregional control and survival outcomes to adjuvant therapy. More …

Meta-analysis of neoadjuvant therapy and its impact in facilitating breast conservation in operable breast cancer

A Karakatsanis, MK Tasoulis, F Wärnberg… - Journal of British …, 2018 - academic.oup.com
Background Neoadjuvant therapy (NAT) for operable breast cancer may facilitate more
breast-conserving surgery (BCS). It seems, however, that this benefit is not being realized …

De-Escalation Surgery in cT3-4 Breast Cancer Patients after Neoadjuvant Therapy: Predictors of Breast Conservation and Comparison of Long-Term Oncological …

C Tinterri, E Barbieri, A Sagona, A Bottini, G Canavese… - Cancers, 2024 - mdpi.com
Simple Summary Neoadjuvant therapy (NAT) has transformed the treatment of advanced
breast cancer (BC), making previously inoperable tumors operable and allowing for the …

Oncological outcome of complete response after neoadjuvant chemotherapy for breast conserving surgery: a systematic review and meta-analysis

X Li, D Dai, B Chen, H Tang, W Wei - World journal of surgical oncology, 2017 - Springer
Background With limited sample sizes and single-institution designs, how complete
response (CR) after neoadjuvant chemotherapy (NAC) influences breast conserving surgery …

Patterns of care in the administration of neo‐adjuvant chemotherapy for breast cancer. A population‐based study

G Vugts, AJG Maaskant‐Braat… - The Breast …, 2016 - Wiley Online Library
Neo‐adjuvant chemotherapy (NAC) is used to facilitate radical surgery for initially
irresectable or locally advanced breast cancer. The indication for NAC has been extended to …

The shifting paradigm for breast cancer surgery in patients undergoing neoadjuvant chemotherapy

O Kantor, G Ajmani, CH Wang, A Datta… - Annals of Surgical …, 2018 - Springer
Introduction Surgical therapy for newly diagnosed breast cancer has changed over the past
decade, but these trends have not been well documented in patients undergoing …