Drug addiction presents as a chronic relapsing disorder characterized by persistent drug‐
seeking and drug‐taking behaviours. Given the significant detrimental effects of this disease …

Drug addiction is a chronically relapsing disorder that has been characterized by (1)
compulsion to seek and take the drug,(2) loss of control in limiting intake, and (3) emergence …

Neurobiologic Advances from the Brain Disease Model of Addiction | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Addiction can be defined in part as a compulsion to use alcohol or other drugs and the
occurrence of withdrawal symptoms when long-term consumption ceases. In addition to …

George F. Koob,* Pietro Paolo Sanna, and Floyd E. Bloom diction (Koob and Le Moal, 1997;
Koob et al., 1998). The underlying molecular and cellular changes that Department of …

Drug addiction manifests as a compulsive drive to take a drug despite serious adverse
consequences. This aberrant behaviour has traditionally been viewed as bad'choices' that …

Drug addiction is a chronic relapsing disorder, and a significant amount of research has
been devoted to understand the factors that contribute to the development, loss of control …

Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems
in the brain that are responsible for drug addiction. Common neurobiological elements are …

RECENT SCIENTIFIC ADVANCES HAVE LED to a greater understanding of the
neurobiological processes that underlie drug abuse and addiction. These suggest that …

Drug addiction is a chronic relapsing disorder characterized by compulsive drug intake, loss
of control over intake, and impairment in social and occupational function. Animal models …