The combination of metformin with morin alleviates hepatic steatosis via modulating hepatic lipid metabolism, hepatic inflammation, brown adipose tissue …
Aim The valuable effects of metformin (MET) and morin (MOR) in the improvement of NAFLD
have been proposed, nevertheless, their combination impacts were not investigated so far …
have been proposed, nevertheless, their combination impacts were not investigated so far …
[HTML][HTML] Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity
Non-alcoholic fatty liver disease (NAFLD) is closely associated with obesity and insulin
resistance. To better understand the pathophysiology of obesity-associated NAFLD, the …
resistance. To better understand the pathophysiology of obesity-associated NAFLD, the …
Combination therapy of metformin and p-coumaric acid mitigates metabolic dysfunction associated with obesity and nonalcoholic fatty liver disease in high-fat diet …
Metformin (MET) has been demonstrated to have favorable impact on nonalcoholic fatty liver
disease (NAFLD); however, the combined effect of this drug with p-coumaric acid (PCA) on …
disease (NAFLD); however, the combined effect of this drug with p-coumaric acid (PCA) on …
Combination of metformin and genistein alleviates non-alcoholic fatty liver disease in high-fat diet-fed mice
F Zamani-Garmsiri, SMR Hashemnia… - The Journal of nutritional …, 2021 - Elsevier
Metformin (MET) and genistein (GEN) have a beneficial role in alleviating non-alcoholic fatty
liver disease (NAFLD), but their combined effect on this disease has not yet been studied …
liver disease (NAFLD), but their combined effect on this disease has not yet been studied …
Combination of metformin and chlorogenic acid attenuates hepatic steatosis and inflammation in high‐fat diet fed mice
F Zamani‐Garmsiri, G Ghasempour, M Aliabadi… - IUBMB …, 2021 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) has become an important health problem in the
world. Natural products, with anti‐inflammatory properties, are potential candidates for …
world. Natural products, with anti‐inflammatory properties, are potential candidates for …
[HTML][HTML] Metformin treatment reverses high fat diet-induced non-alcoholic fatty liver diseases and dyslipidemia by stimulating multiple antioxidant and anti …
Purpose This current study investigated the effect of metformin treatment on hepatic
oxidative stress and inflammation associated with nonalcoholic fatty liver disease (NADLD) …
oxidative stress and inflammation associated with nonalcoholic fatty liver disease (NADLD) …
Metformin prevents liver tumorigenesis induced by high-fat diet in C57Bl/6 mice
K Tajima, A Nakamura, J Shirakawa… - American Journal …, 2013 - journals.physiology.org
The prevalence of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis
(NASH) is increasing with the growing epidemics of obesity and diabetes. NAFLD …
(NASH) is increasing with the growing epidemics of obesity and diabetes. NAFLD …
Interaction between metformin and leucine in reducing hyperlipidemia and hepatic lipid accumulation in diet-induced obese mice
Abstract Background Leucine stimulates Sirt1 and AMPK signaling in vitro and in vivo. Since
metformin converges on the same pathway, we have tested the ability of leucine to amplify …
metformin converges on the same pathway, we have tested the ability of leucine to amplify …
[HTML][HTML] Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD‑induced obese mice
M Li, A Sharma, C Yin, X Tan… - Molecular medicine …, 2017 - spandidos-publications.com
The present study aimed to investigate the effect of metformin on the induction of autophagy
in the liver and adipose tissues of a mouse model of obesity. C57BL/6J mice were fed a high …
in the liver and adipose tissues of a mouse model of obesity. C57BL/6J mice were fed a high …
Morin attenuates hepatic insulin resistance in high-fat-diet-induced obese mice
J Naowaboot, S Wannasiri, P Pannangpetch - Journal of physiology and …, 2016 - Springer
Morin is a natural bioflavonoid that exhibits antioxidant and anti-inflammatory properties.
The present study was designed to evaluate the effect of morin on insulin resistance …
The present study was designed to evaluate the effect of morin on insulin resistance …