The present study aimed to investigate the effect of metformin on the induction of autophagy
in the liver and adipose tissues of a mouse model of obesity. C57BL/6J mice were fed a high …

Morin is a natural bioflavonoid that exhibits antioxidant and anti-inflammatory properties.
The present study was designed to evaluate the effect of morin on insulin resistance …

Gemfibrozil (GEM) is a member of the fibrate class of lipid‑lowering pharmaceuticals and
has been widely used in the therapy of different forms of hyperlipidemia and …

Background Treatment with metformin, the biguanide of hepatic insulin sensitizer, in patients
with non-alcoholic fatty liver disease (NAFLD) has been reported with contradictory findings …

Obesity and its associated metabolic disorders are related to the onset of fatty liver and the
balance of white adipose tissue (WAT) and brown adipose tissue (BAT). We hypothesized …

The aim of this study was to examine the therapeutic effect of oxymatrine, a monomer
isolated from the medicinal plant Sophora flavescens Ait, on the hepatic lipid metabolism in …

Metformin (Met) and lactoferrin (Lf) both exhibit beneficial effects on body weight
management and lipid accumulation. However, the synergistical action of Met and Lf …

Background Non-alcoholic fatty liver disease (NAFLD) is one of the primary causes of
chronic liver disease and is closely linked to insulin resistance, type 2 diabetes mellitus …

Background/Aims: Fisetin is a naturally abundant flavonoid isolated from various fruits and
vegetables that was recently identified to have potential biological functions in improving …

Weight loss is recommended for patients with nonalcoholic fatty liver disease (NAFLD),
while metformin may lower liver enzymes in type 2 diabetics. Yet, the efficacy of the …