[HTML][HTML] The efficacy of immunomodulators in the prevention and suppression of anti-drug antibodies to anti-tumor necrosis factor therapy in inflammatory bowel …

FS Fousekis, K Papamichael, G Kourtis… - Annals of …, 2022 - ncbi.nlm.nih.gov
The development of biological agents against tumor necrosis factor (TNF) has revolutionized
the management of inflammatory bowel disease (IBD), frequently achieving induction and …

The risk of lymphoma in the treatment of inflammatory bowel disease with immunosuppressive agents

JH Kwon, RJ Farrell - Critical reviews in oncology/hematology, 2005 - Elsevier
Immunosuppressive agents have become an established part of the therapeutic
armamentarium for inflammatory bowel disease (IBD). However, when used in transplant …

Targeting TNF-α for the treatment of inflammatory bowel disease

T Billiet, P Rutgeerts, M Ferrante… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: The advent of tumor necrosis factor (TNF) antagonists represented a radical
change in the management of inflammatory bowel disease (IBD). Both in short-and long …

Safety of infliximab in Crohn's disease: a large single-center experience

H Hamzaoglu, J Cooper, M Alsahli… - Inflammatory bowel …, 2010 - academic.oup.com
Background The aim of this study was to evaluate the short-and long-term safety experience
of infliximab treatment in patients with Crohn's disease (CD) in clinical practice. Methods The …

Anti-TNF agents in Crohn's disease

GV Assche, P Rutgeerts - Expert opinion on investigational drugs, 2000 - Taylor & Francis
The current treatment of Crohn's disease is limited by a lack of long-term efficacy of
corticosteroid therapy and the associated side effects. Biological treatment strategies aimed …

Understanding the complications of anti‐tumor necrosis factor therapy in East Asian patients with inflammatory bowel disease

JH Cheon - Journal of Gastroenterology and Hepatology, 2017 - Wiley Online Library
Remarkable advances have been made in the treatment of inflammatory bowel disease
since the introduction of anti‐tumor necrosis factor‐α agents, especially for patients who are …

Clinical outcome after anti‐tumour necrosis factor therapy discontinuation in 1000 patients with inflammatory bowel disease: the EVODIS long‐term study

MJ Casanova, M Chaparro, Ó Nantes… - Alimentary …, 2021 - Wiley Online Library
Background The long‐term outcome of patients after antitumour necrosis factor alpha (anti‐
TNF) discontinuation is not well known. Aims To assess the risk of relapse in the long‐term …

Systematic review: factors associated with relapse of inflammatory bowel disease after discontinuation of anti‐TNF therapy

JP Gisbert, AC Marín… - Alimentary pharmacology & …, 2015 - Wiley Online Library
Background The discontinuation of anti‐tumour necrosis factor (anti‐TNF) treatment in
inflammatory bowel disease (IBD) patients in remission could be considered. Aim To …

Management of inflammatory bowel disease with infliximab and other anti-tumor necrosis factor alpha therapies

F Magro, F Portela - BioDrugs, 2010 - Springer
Inflammatory bowel disease (IBD), most commonly referring to Crohn's disease and
ulcerative colitis, is a chronic and disabling condition with an increasing incidence in …

Novel pharmacological therapy in inflammatory bowel diseases: beyond anti-tumor necrosis factor

C Pagnini, TT Pizarro, F Cominelli - Frontiers in Pharmacology, 2019 - frontiersin.org
Inflammatory bowel diseases (IBDs) are chronic conditions of the gastrointestinal tract in
which dysregulated immune responses cause persistent inflammation of the gut mucosa …