TNF inhibitors and risk of malignancy in patients with inflammatory bowel diseases: a systematic review

M Muller, F D'Amico, S Bonovas… - Journal of Crohn's …, 2021 - academic.oup.com
Abstract Background and Aims The association between tumour necrosis factor inhibitors
[TNFi] and malignancy in patients with inflammatory bowel disease [IBD] is not well …

[HTML][HTML] Risk of post-operative complications associated with anti-TNF therapy in inflammatory bowel disease

T Ali, L Yun, DT Rubin - World journal of gastroenterology: WJG, 2012 - ncbi.nlm.nih.gov
There have been increasing concerns regarding the safety of perioperative anti-tumour
necrosis factor (anti-TNF) α agents. We performed a literature review to evaluate the post …

Infliximab in inflammatory bowel disease: clinical outcome in a population based cohort from Stockholm County

T Ljung, P Karlen, D Schmidt, PM Hellström, A Lapidus… - Gut, 2004 - gut.bmj.com
Background: Several placebo controlled studies have demonstrated the efficacy of infliximab
in inflammatory bowel disease (IBD) but the potential toxicity of this new biological …

Comparative risk of serious infections with biologic and/or immunosuppressive therapy in patients with inflammatory bowel diseases: a systematic review and meta …

S Singh, A Facciorusso, PS Dulai, V Jairath… - Clinical …, 2020 - Elsevier
Background & Aims We performed a systematic review and meta-analysis to evaluate the
comparative risk of serious infections with tumor necrosis factor (TNF) antagonists, non-TNF …

Combined biologic and immunomodulatory therapy is superior to monotherapy for decreasing the risk of inflammatory bowel disease-related complications

LE Targownik, EI Benchimol… - Journal of Crohn's …, 2020 - academic.oup.com
Abstract Background and Aims The combination of infliximab and azathioprine is more
efficacious than either therapy alone for Crohn's disease [CD] and ulcerative colitis [UC] …

minimizing tuberculosis during anti‐tumour necrosis factor‐alpha treatment of inflammatory bowel disease

VS Theis, JM Rhodes - Alimentary pharmacology & …, 2008 - Wiley Online Library
Background Tumour necrosis factor (TNF)‐alpha inhibitors are a major advance in the
management of inflammatory bowel disease but increase the risk for tuberculosis (TB). Aim …

Anti-TNF drug and antidrug antibody level monitoring in IBD: a practical guide

P Hendy, A Hart, P Irving - Frontline gastroenterology, 2016 - fg.bmj.com
The antitumour necrosis factor (TNF) medications, adalimumab and infliximab, play an
important role in the management of both Crohn's disease and ulcerative colitis. For those in …

Discontinuation of anti-tumor necrosis factor therapy in inflammatory bowel disease patients: a prospective observation

M Bortlik, D Duricova, N Machkova… - Scandinavian Journal …, 2016 - Taylor & Francis
Background: Discontinuation of anti-TNF therapy in patients with inflammatory bowel
diseases (IBD) in remission remains a controversial issue. The aims of our study were to …

[HTML][HTML] A guide to preparation of patients with inflammatory bowel diseases for anti-TNF-α therapy

JMF Chebli, PD Gaburri, LA Chebli… - … medical journal of …, 2014 - ncbi.nlm.nih.gov
Current therapy of moderate-to-severe inflammatory bowel disease (IBD) often involves the
use of anti-tumor necrosis factor alpha (TNF-α) agents. Although very effective, theses …

Risks and benefits of infliximab for the treatment of Crohn's disease

CA Siegel, C Hur, JR Korzenik, GS Gazelle… - Clinical …, 2006 - Elsevier
Background & Aims: Infliximab is effective for the treatment of active Crohn's disease.
However, rare but serious complications related to infliximab therapy including lymphoma …