Safety of infliximab in 10 years of clinical practice

S O'Donnell, S Murphy, MM Anwar… - European journal of …, 2011 - journals.lww.com
Assessment of the long-term safety of anti-tumour necrosis factor therapies is vital for the
safe treatment of inflammatory bowel disease, a disease affecting a young cohort of patients …

Use of infliximab in particular clinical settings: management based on current evidence

A Papa, G Mocci, M Bonizzi, C Felice… - Official journal of the …, 2009 - journals.lww.com
With the increasingly widespread use of the anti-tumor necrosis factor-α agent infliximab for
the treatment of Crohn's disease and ulcerative colitis, there have been some concerns …

Tumor necrosis factor blockade for treatment of inflammatory bowel disease: efficacy and safety

B Ngo, CP Farrell, M Barr, K Wolov… - Current Molecular …, 2010 - ingentaconnect.com
Inflammatory bowel disease (IBD), including Crohn's Disease (CD) and Ulcerative Colitis
(UC), is characterized by inflammation of the gastrointestinal tract. In UC, inflammation is …

Efficacy of TNF antagonists beyond one year in adult and pediatric inflammatory bowel diseases: a systematic review

A Oussalah, S Danese, L Peyrin-Biroulet - Current drug targets, 2010 - ingentaconnect.com
The introduction in the mid-1990s of tumor necrosis factor (TNF) antagonists changed the
treatment of inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis (UC) …

[HTML][HTML] Management of non-response and loss of response to anti-tumor necrosis factor therapy in inflammatory bowel disease

J Marsal, M Barreiro-de Acosta, I Blumenstein… - Frontiers in …, 2022 - frontiersin.org
Anti-tumor necrosis factor (anti-TNF) therapy has been successfully used as first-line
biologic treatment for moderate-to-severe inflammatory bowel disease (IBD), in both “step …

Loss of response to anti-TNFs: definition, epidemiology, and management

G Roda, B Jharap, N Neeraj… - Clinical and translational …, 2016 - journals.lww.com
Tumor necrosis factor-α (TNFα) antagonists have advanced the management of
inflammatory bowel diseases patients leading to an improvement of patient's quality of life …

consensus statements on therapeutic drug monitoring of anti‐tumour necrosis factor therapy in inflammatory bowel diseases

N Mitrev, N Vande Casteele, CH Seow… - Alimentary …, 2017 - Wiley Online Library
Background Therapeutic drug monitoring (TDM) in inflammatory bowel disease (IBD)
patients receiving anti‐tumour necrosis factor (TNF) agents can help optimise outcomes …

Use of biological molecules in the treatment of inflammatory bowel disease

OH Nielsen, JB Seidelin, LK Munck… - Journal of internal …, 2011 - Wiley Online Library
Nielsen OH, Seidelin JB, Munck LK, Rogler G (Herlev Hospital, University of Copenhagen,
Copenhagen; Køge Hospital, University of Copenhagen, Copenhagen, Denmark; and …

Increased mortality rates with prolonged corticosteroid therapy when compared with antitumor necrosis factor-α-directed therapy for inflammatory bowel disease

JD Lewis, FI Scott, CM Brensinger, JA Roy… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel
diseases (IBD) that compromise quality of life and may increase mortality. This study …

Update on anti-tumor necrosis factor agents and other new drugs for inflammatory bowel disease

BL Cohen, DB Sachar - Bmj, 2017 - bmj.com
The treatment of inflammatory bowel disease (IBD)—ulcerative colitis (UC) and Crohn's
disease (CD)—has evolved beyond surgery with the introduction of biologic agents …