Improving outcomes for patients with relapsed multiple myeloma: challenges and considerations of current and emerging treatment options

K Ramasamy, F Gay, K Weisel, S Zweegman… - Blood Reviews, 2021 - Elsevier
Despite the recent introduction of new therapies for multiple myeloma (MM), it remains an
incurable disease. As MM progresses, patients experience cycles of relapse and remission …

Current treatment landscape for relapsed and/or refractory multiple myeloma

MA Dimopoulos, PG Richardson, P Moreau… - Nature reviews Clinical …, 2015 - nature.com
Recent developments in the treatment of multiple myeloma have led to improvements in
response rates and to increased survival; however, relapse is inevitable in almost all …

Management of relapsed and relapsed/refractory multiple myeloma

JP Laubach, CS Mitsiades, A Mahindra… - Journal of the National …, 2011 - jnccn.org
Despite significant progress in the treatment of multiple myeloma (MM) over the past
decade, this disease remains incurable and almost all patients ultimately experience …

The future of therapy for relapsed/refractory multiple myeloma: emerging agents and novel treatment strategies

P Moreau - Seminars in hematology, 2012 - Elsevier
Treatment of relapsed or refractory multiple myeloma (MM) continues to present a
therapeutic challenge. The immunomodulatory drugs (IMiDs) thalidomide and lenalidomide …

Treatment of relapsed multiple myeloma: Evidence-based recommendations

C Durer, S Durer, S Lee, R Chakraborty, MN Malik… - Blood Reviews, 2020 - Elsevier
The practice of choosing the next best therapy for patients with relapsed and/or refractory
multiple myeloma (RRMM) is becoming increasingly complex. There is no clear consensus …

Gaps and opportunities in the treatment of relapsed-refractory multiple myeloma: Consensus recommendations of the NCI Multiple Myeloma Steering Committee

S Kumar, L Baizer, NS Callander, SA Giralt… - Blood cancer …, 2022 - nature.com
A wide variety of new therapeutic options for Multiple Myeloma (MM) have recently become
available, extending progression-free and overall survival for patients in meaningful ways …

Relapsed/refractory multiple myeloma: A review of available therapies and clinical scenarios encountered in myeloma relapse

P Bhatt, C Kloock, R Comenzo - Current Oncology, 2023 - mdpi.com
Multiple myeloma remains an incurable disease with the usual disease course requiring
induction therapy, autologous stem cell transplantation for eligible patients, and long-term …

Management strategies for relapsed/refractory multiple myeloma: current clinical perspectives

A Jakubowiak - Seminars in hematology, 2012 - Elsevier
In the last decade, the introduction of novel agents including the immunomodulatory drugs
thalidomide and lenalidomide, and the first-in-class proteasome inhibitor bortezomib, has …

[HTML][HTML] A question of class: treatment options for patients with relapsed and/or refractory multiple myeloma

G Cook, S Zweegman, MV Mateos, F Suzan… - Critical Reviews in …, 2018 - Elsevier
Multiple classes of agent with distinct mechanisms of action are now available for the
treatment of patients with relapsed and/or refractory multiple myeloma (RRMM), including …

Current strategies for treatment of relapsed/refractory multiple myeloma

JP Laubach, PM Voorhees, H Hassoun… - Expert review of …, 2014 - Taylor & Francis
In spite of significant advances in the management of multiple myeloma (MM), the disease
remains incurable and nearly all patients ultimately relapse and require salvage …