Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics
BA Graver, N Chakravarty, KV Solomon - Trends in Biotechnology, 2023 - cell.com
Prokaryotic Argonautes (pAgos) are an emerging class of programmable endonucleases
that are believed to be more flexible than existing CRISPR–Cas systems and have …
that are believed to be more flexible than existing CRISPR–Cas systems and have …
NgAgo possesses guided DNA nicking activity
Prokaryotic Argonautes (pAgos) have been proposed as more flexible tools for gene-editing
as they do not require sequence motifs adjacent to their targets for function, unlike popular …
as they do not require sequence motifs adjacent to their targets for function, unlike popular …
Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea
A Kuzmenko, D Yudin, S Ryazansky… - Nucleic acids …, 2019 - academic.oup.com
Argonaute (Ago) proteins are key players in RNA interference in eukaryotes, where they
function as RNA-guided RNA endonucleases. Prokaryotic Argonautes (pAgos) are much …
function as RNA-guided RNA endonucleases. Prokaryotic Argonautes (pAgos) are much …
Argonaute proteins from human gastrointestinal bacteria catalyze DNA-guided cleavage of single-and double-stranded DNA at 37° C
Dear Editor, Eukaryotic Argonaute (eAgos) proteins are the key players in RNA interference
(RNAi) pathways by functioning as an RNA-guided RNA endonucleases 1. The homologous …
(RNAi) pathways by functioning as an RNA-guided RNA endonucleases 1. The homologous …
DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute
Prokaryotic Argonaute proteins (pAgos) constitute a diverse group of endonucleases of
which some mediate host defense by utilizing small interfering DNA guides (siDNA) to …
which some mediate host defense by utilizing small interfering DNA guides (siDNA) to …
A programmable omnipotent Argonaute nuclease from mesophilic bacteria Kurthia massiliensis
Y Liu, W Li, X Jiang, Y Wang, Z Zhang… - Nucleic acids …, 2021 - academic.oup.com
Argonaute (Ago) proteins are conserved nucleic acid-guided proteins present in all domains
of life. Eukaryotic Argonaute proteins (eAgos) are key players in RNA interference pathways …
of life. Eukaryotic Argonaute proteins (eAgos) are key players in RNA interference pathways …
Single-stranded binding proteins and helicase enhance the activity of prokaryotic argonautes in vitro
Prokaryotic argonautes are a unique class of nucleic acid-guided endonucleases putatively
involved in cellular defense against foreign genetic elements. While their eukaryotic …
involved in cellular defense against foreign genetic elements. While their eukaryotic …
Specific targeting of plasmids with Argonaute enables genome editing
D Esyunina, A Okhtienko, A Olina… - Nucleic Acids …, 2023 - academic.oup.com
Prokaryotic Argonautes (pAgos) are programmable nucleases involved in cell defense
against invading DNA. In vitro, pAgos can bind small single-stranded guide DNAs to …
against invading DNA. In vitro, pAgos can bind small single-stranded guide DNAs to …
A programmable pAgo nuclease with RNA target preference from the psychrotolerant bacterium Mucilaginibacter paludis
W Li, Y Liu, R He, L Wang, Y Wang, W Zeng… - Nucleic acids …, 2022 - academic.oup.com
Argonaute (Ago) proteins are programmable nucleases found in eukaryotes and
prokaryotes. Prokaryotic Agos (pAgos) share a high degree of structural homology with …
prokaryotes. Prokaryotic Agos (pAgos) share a high degree of structural homology with …
A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis
E Kropocheva, A Kuzmenko, AA Aravin… - Nucleic acids …, 2021 - academic.oup.com
Argonaute proteins are programmable nucleases that are found in both eukaryotes and
prokaryotes and provide defense against invading genetic elements. Although some …
prokaryotes and provide defense against invading genetic elements. Although some …