[HTML][HTML] Modulation of pulmonary toxicity in metabolic syndrome due to variations in iron oxide nanoparticle-biocorona composition

L Xia, S Alqahtani, CR Ferreira, UK Aryal, K Biggs… - Nanomaterials, 2022 - mdpi.com
Nanoparticles (NPs) interact with biomolecules by forming a biocorona (BC) on their surface
after introduction into the body and alter cell interactions and toxicity. Metabolic syndrome …

From the cover: disease-induced disparities in formation of the nanoparticle-biocorona and the toxicological consequences

JH Shannahan, KS Fritz, AJ Raghavendra… - Toxicological …, 2016 - academic.oup.com
Nanoparticle (NP) association with macromolecules in a physiological environment forms a
biocorona (BC), which alters NP distribution, activity, and toxicity. While BC formation is …

[HTML][HTML] Altered formation of the iron oxide nanoparticle-biocorona due to individual variability and exercise

LM Kobos, SXF Adamson, S Evans, TP Gavin… - Environmental …, 2018 - Elsevier
Nanoparticles (NPs), introduced into a biological environment, accumulate a coating of
biomolecules or biocorona (BC). Although the BC has toxicological and pharmacological …

Experimental challenges regarding the in vitro investigation of the nanoparticle-biocorona in disease states

SXF Adamson, Z Lin, R Chen, L Kobos, J Shannahan - Toxicology in Vitro, 2018 - Elsevier
Toxicological evaluation of nanoparticles (NPs) requires the utilization of in vitro techniques
due to their number and diverse properties. Cell culture systems are often lacking in their …

Long-term pulmonary iron oxide nanoparticles exposure disrupts hepatic iron-lipid homeostasis and increases plaque vulnerability in ApoE−/− mice

Z Yan, Z Liu, B Yang, X Zhu, E Song, Y Song - Environmental Pollution, 2024 - Elsevier
Iron oxide nanoparticles (Fe 3 O 4 NPs) have attracted great attention due to their extensive
applications, which warranted their environmental concerns. Although recent advances …

Synthesis, characterization and toxicological evaluation of iron oxide nanoparticles in human lung alveolar epithelial cells

S Dwivedi, MA Siddiqui, NN Farshori, M Ahamed… - Colloids and Surfaces B …, 2014 - Elsevier
The present investigation was aimed to characterize the synthesized iron oxide
nanoparticles (Fe 3 O 4-NPs) and to assess their cytotoxicity and oxidative stress in human …

Internalization of carbon black and maghemite iron oxide nanoparticle mixtures leads to oxidant production

JM Berg, S Ho, W Hwang, R Zebda… - Chemical Research …, 2010 - ACS Publications
The risk of potential human exposure to mixed nanomaterials in consumer, occupational,
and medicinal settings is increasing as nanomaterials enter both the workplace and the …

Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis

MT Zhu, B Wang, Y Wang, L Yuan, HJ Wang, M Wang… - Toxicology letters, 2011 - Elsevier
More recently, the correlation between exposure to nanoparticles and cardiovascular
diseases is of particular concern in nanotoxicology related fields. Nanoparticle-triggered …

[HTML][HTML] Ultrasmall iron oxide nanoparticles cause significant toxicity by specifically inducing acute oxidative stress to multiple organs

L Wu, W Wen, X Wang, D Huang, J Cao, X Qi… - Particle and Fibre …, 2022 - Springer
Background Iron oxide nanoparticles have been approved by food and drug administration
for clinical application as magnetic resonance imaging (MRI) and are considered to be a …

Chronic pulmonary exposure of iron oxide nanoparticls induced Th1-type immune response accompanying suppression of antigen-presenting function (IRM12P. 647)

EJ Park, S Lee, K Lee, Y Kim, BS Lee - The Journal of Immunology, 2015 - journals.aai.org
Accumulated evidence shows that pulmonary nanoparticles induce adverse health effects
by modulating immune system in the body. In this study, we investigated local and systemic …