Background: Sleep disturbances have long been associated with Alzheimer's disease (AD),
and there is a growing interest in how these disturbances might impact AD pathophysiology …

Aims Insufficient sleep has been found to result in varying degrees of cognitive impairment
and emotional changes. Sleep was reported probably responsible for cleaning metabolic …

Sleep is a behavioral phenomenon conserved among mammals and some invertebrates,
yet the biological functions of sleep are still being elucidated. In humans, sleep time …

Abstract Study Objectives: Sleep fragmentation (SF) is an integral feature of sleep apnea
and other prevalent sleep disorders. Although the effect of repetitive arousals on cognitive …

Background The amyloid hypothesis predicts that increased production or decreased
clearance of β-amyloid (Aβ) leads to amyloidosis, which ultimately culminates in Alzheimer …

Sleep disturbance is a recognized risk factor for Alzheimer's disease (AD), but the
underlying micro-pathological evidence remains limited. To bridge this gap, we established …

Abstract Study Objectives: Emerging evidence suggests a role for sleep in contributing to the
progression of Alzheimer disease (AD). Slow wave sleep (SWS) is the stage during which …

Sleep disturbances are a common early symptom of neurodegenerative diseases, including
Alzheimer's disease (AD) and other age-related dementias, and emerging evidence …

Alzheimer's disease (AD) is the most common cause of dementia and currently there are no
effective disease-modifying treatments available. Hallmark symptoms of AD include …

Sleep has an important role for long-term memory consolidation. As deficits in learning and
memory are clinical characteristics of Alzheimer's disease (AD), it has been suggested that …