Membrane-active peptides (MAPs) exhibit great potential in biomedical applications due to
their unique ability to overcome the cell membrane barrier. However, the interactions …

Membrane curvature plays a crucial role in the realization of many cellular membrane
functions such as signaling and trafficking. Here, using coarse-grained molecular dynamics …

Membrane curvature and lipid composition plays a critical role in interchanging of matter
and energy in cells. Peptide curvature sensors are known to activate signaling pathways …

Extensive effort has been devoted to developing new clinical therapies based on membrane-
active peptides (MAPs). Previous models on the membrane action mechanisms of these …

The interplay of membrane proteins is vital for many biological processes, such as cellular
transport, cell division, and signal transduction between nerve cells. Theoretical …

We investigated the deformation of lipid bilayer membrane by cell‐penetrating peptide using
coarse‐grained molecular dynamics simulation. The simulations have been performed with …

Membrane curvature and lipid composition regulates important biological processes within a
cell. Currently, several proteins have been reported to sense and/or induce membrane …

Pore formation by membrane-active antimicrobial peptides is a classic strategy of pathogen
inactivation through disruption of membrane biochemical gradients. It remains unknown why …

It is increasingly recognized that membrane curvature plays an important role in various
cellular activities such as signaling and trafficking, as well as key issues involving health and …

Amphipathic α-helical peptides are often ascribed an ability to induce curvature stress in
lipid membranes. This may lead directly to a bending deformation of the host membrane, or …