Oxidative potential versus biological effects: a review on the relevance of cell-free/abiotic assays as predictors of toxicity from airborne particulate matter

J Øvrevik - International journal of molecular sciences, 2019 - mdpi.com
Background and Objectives: The oxidative potential (OP) of particulate matter (PM) in cell-
free/abiotic systems have been suggested as a possible measure of their biological …

Review of acellular assays of ambient particulate matter oxidative potential: methods and relationships with composition, sources, and health effects

JT Bates, T Fang, V Verma, L Zeng… - … science & technology, 2019 - ACS Publications
Oxidative stress is a potential mechanism of action for particulate matter (PM) toxicity and
can occur when the body's antioxidant capacity cannot counteract or detoxify harmful effects …

Particulate matter (PM) oxidative potential: Measurement methods and links to PM physicochemical characteristics and health effects

L He, J Zhang - Critical Reviews in Environmental Science and …, 2023 - Taylor & Francis
It has been widely accepted that the induction of reactive oxygen species (ROS) is an
important pathophysiologic pathway linking particulate matter (PM) exposure and adverse …

Ambient particulate matter oxidative potential: Chemical determinants, associated health effects, and strategies for risk management

D Gao, S Ripley, S Weichenthal, KJG Pollitt - Free Radical Biology and …, 2020 - Elsevier
Exposure to ambient air pollution has an adverse influence on human health. There is
increasing evidence that oxidative potential (OP), the capacity of airborne pollutants to …

Evaluating the molecular assays for measuring the oxidative potential of particulate matter

F Hedayat, S Stevanovic, B Miljevic, S Bottle… - 2015 - dro.deakin.edu.au
Several cell-free assays are currently used to quantify and detect the reactive oxygen
species (ROS). All of them have certain limitations, do not provide direct comparison of …

Global perspective on the oxidative potential of airborne particulate matter: a synthesis of research findings

A Saffari, N Daher, MM Shafer… - … science & technology, 2014 - ACS Publications
An emerging hypothesis in the field of air pollution is that oxidative stress is one of the
important pathways leading to adverse health effects of airborne particulate matter (PM). To …

[HTML][HTML] Characterisation of the correlations between oxidative potential and in vitro biological effects of PM10 at three sites in the central Mediterranean

MR Guascito, MG Lionetto, F Mazzotta, M Conte… - Journal of Hazardous …, 2023 - Elsevier
Atmospheric particulate matter (PM) is one of the major risks for global health. The exact
mechanisms of toxicity are still not completely understood leading to contrasting results …

Lung antioxidant depletion: a predictive indicator of cellular stress induced by ambient fine particles

B Crobeddu, I Baudrimont, J Deweirdt… - Environmental …, 2020 - ACS Publications
Regulations on ambient particulate matter (PM) are becoming more stringent because of
adverse health effects arising from PM exposure. PM-induced oxidant production is a key …

[HTML][HTML] Comparison between five acellular oxidative potential measurement assays performed with detailed chemistry on samples from the city of Chamonix …

A Calas, G Uzu, FJ Kelly, S Houdier… - Atmospheric …, 2018 - acp.copernicus.org
Many studies have demonstrated associations between exposure to ambient particulate
matter (PM) and adverse health outcomes in humans that can be explained by PM capacity …

A critical review of assays for hazardous components of air pollution

HJ Forman, CE Finch - Free Radical Biology and Medicine, 2018 - Elsevier
Increased mortality and diverse morbidities are globally associated with exposure to
ambient air pollution (AAP), cigarette smoke (CS), and household air pollution (HAP). The …