Anti-cancer and anti-inflammatory activities of apigenin nanoencapsulated in dairy proteins

S Hong - 2020 - trace.tennessee.edu
Dietary polyphenols such as apigenin are the secondary plant metabolites reported to
reduce incidence of many chronic diseases including cancers and chronic inflammation …

[HTML][HTML] Nanoencapsulation of apigenin with whey protein isolate: Physicochemical properties, in vitro activity against colorectal cancer cells, and bioavailability

S Hong, VP Dia, SJ Baek, Q Zhong - Lwt, 2022 - Elsevier
Incorporating lipophilic phytochemicals with anti-cancer activities in functional beverages
requires an appropriate nanoencapsulation technology. The present objective was to …

Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages

S Hong, VP Dia, Q Zhong - International journal of biological …, 2021 - Elsevier
Dietary polyphenols are potential anti-inflammatory agents, and their combinations with
enhanced biological activities may lower toxicity and side effects. The objective of this work …

[HTML][HTML] The effect of encapsulated apigenin nanoparticles on HePG-2 cells through regulation of P53

MM Mabrouk Zayed, HA Sahyon, NAN Hanafy… - Pharmaceutics, 2022 - mdpi.com
Apigenin (Ap) is one of the most important natural flavonoids that has potent anticancer
activity. This study was designed, for the first time, to load Ap into chitosan to improve its …

Preparation, characterization and antitumor activity evaluation of apigenin nanoparticles by the liquid antisolvent precipitation technique

W Wu, Y Zu, L Wang, L Wang, H Wang, Y Li, M Wu… - Drug …, 2017 - Taylor & Francis
The present work aimed to apply the liquid antisolvent precipitation (LAP) method for
preparing the apigenin nanoparticles and thereby improving the solubility and bioavailability …

[PDF][PDF] The Effect of Encapsulated Apigenin Nanoparticles on HePG-2 Cells through Regulation of P53. Pharmaceutics 2022, 14, 1160

MMM Zayed, HA Sahyon, NAN Hanafy, MA El-Kemary - 2022 - researchgate.net
Apigenin (Ap) is one of the most important natural flavonoids that has potent anticancer
activity. This study was designed, for the first time, to load Ap into chitosan to improve its …

[PDF][PDF] The Effect of Encapsulated Apigenin Nanoparticles on HePG-2 Cells through Regulation of P53. Pharmaceutics 2022, 14, 1160

MM Mabrouk Zayed, HA Sahyon, NAN Hanafy… - 2022 - academia.edu
Apigenin (Ap) is one of the most important natural flavonoids that has potent anticancer
activity. This study was designed, for the first time, to load Ap into chitosan to improve its …

Zein-whey protein isolate-carboxymethyl cellulose complex as carrier of apigenin via pH-driven method: Fabrication, characterization, stability, and in vitro release …

Q Liu, Y Li, Y Zhou, L Jiang, Q Lyu, G Liu, X Wang… - Food Chemistry, 2022 - Elsevier
The poor water solubility of apigenin limits its application feasibility in food and medicine. To
address this issue, this study successfully prepared apigenin-loaded zein composite …

[HTML][HTML] Recent advancement in bioeffect, metabolism, stability, and delivery systems of apigenin, a natural flavonoid compound: Challenges and perspectives

P Chen, F Chen, ZL Guo, J Lei, B Zhou - Frontiers in Nutrition, 2023 - ncbi.nlm.nih.gov
Apigenin is a bioflavonoid compound that is widely present in dietary plant foods and
possesses biological activities that protect against immune, cardiovascular, and …

[HTML][HTML] Encapsulation of hydrophobic apigenin into small unilamellar liposomes coated with chitosan through ethanol injection and spray drying

SS Ang, YY Thoo, LF Siow - Food and bioprocess technology, 2024 - Springer
Despite the multiple health benefits, natural flavonoid apigenin has poor aqueous solubility
that restricts its delivery in foods. This study investigated the potential of spray-dried chitosan …