Effects of prenatal stress on behavioural and neurodevelopmental outcomes are altered by maternal separation in the neonatal period

GK Crombie, HK Palliser, JC Shaw… - …, 2021 - Elsevier
Background Chronic psychosocial stress during pregnancy and/or after birth, and the
associated elevation in cortisol, is linked with the onset of behavioural disorders in …

Effects of prenatal stress on fetal neurodevelopment and responses to maternal neurosteroid treatment in guinea pigs

GA Bennett, HK Palliser, B Saxby, DW Walker… - Developmental …, 2013 - karger.com
Background: Maternal psychosocial stress during pregnancy is associated with adverse
neonatal outcomes. These outcomes result from changes in fetal brain development and …

Evaluating changes in GABAergic and glutamatergic pathways in early life following prenatal stress and postnatal neurosteroid supplementation

GK Crombie, HK Palliser, JC Shaw… - …, 2022 - Elsevier
Background A correct balance of activity of the GABA and glutamate systems is vital for
optimal neurodevelopment and general CNS function, and the dysregulation of this balance …

Prenatal stress alters hippocampal neuroglia and increases anxiety in childhood

GA Bennett, HK Palliser, JC Shaw, D Walker… - Developmental …, 2015 - karger.com
Prenatal stress has been associated with detrimental outcomes of pregnancy, including
altered brain development leading to behavioural pathologies. The neurosteroid …

How early maternal deprivation changes the brain and behavior?

M Čater, G Majdič - European journal of neuroscience, 2022 - Wiley Online Library
Early life stress can adversely influence brain development and reprogram brain function
and consequently behavior in adult life. Adequate maternal care in early childhood is …

Increased anxiety-like phenotype in female guinea pigs following reduced neurosteroid exposure in utero

AL Cumberland, HK Palliser, GK Crombie… - International Journal of …, 2017 - Elsevier
Neurosteroids are essential for aiding proper fetal neurodevelopment. Pregnancy
compromises such as preterm birth, prenatal stress and intrauterine growth restriction are …

Effects of combined IUGR and prenatal stress on the development of the hippocampus in a fetal guinea pig model

AL Cumberland, HK Palliser, P Rani… - … origins of health and …, 2017 - cambridge.org
Intrauterine growth restriction (IUGR) and maternal stress during pregnancy are two
compromises that negatively impact neurodevelopment and increase the risk of developing …

Severity and timing: How prenatal stress exposure affects glial developmental, emotional behavioural and plasma neurosteroid responses in guinea pig offspring

GA Bennett, HK Palliser, D Walker, J Hirst - Psychoneuroendocrinology, 2016 - Elsevier
Prenatal stress has been associated with a variety of developmental changes in offspring,
notably those associated with brain development and subsequent risk for neuropathologies …

Neurobehavioral abnormalities following prenatal psychosocial stress are differentially modulated by maternal environment

SP Zoubovsky, MT Williams, S Hoseus… - Translational …, 2022 - nature.com
Prenatal stress (PS) is associated with increased vulnerability to affective disorders.
Transplacental glucocorticoid passage and stress-induced maternal environment alterations …

Maternal stress in pregnancy affects myelination and neurosteroid regulatory pathways in the guinea pig cerebellum

GA Bennett, HK Palliser, JC Shaw, KL Palazzi… - Stress, 2017 - Taylor & Francis
Prenatal stress predisposes offspring to behavioral pathologies. These may be attributed to
effects on cerebellar neurosteroids and GABAergic inhibitory signaling, which can be linked …