Background: Salidroside, one of the main active ingredients in Fructus Ligustri Lucidi (FLL),
is well demonstrated to exert anti-osteoporotic effect. However, the plasma pharmacokinetic …

Background: Fructus Ligustri Lucidi (FLL) has now attracted increasing attention as an
alternative medicine in the prevention and treatment of osteoporosis. This study aimed to …

A sensitive and specific liquid chromatography–electrospray ionization-mass spectrometry
(LC–ESI-MS) method has been developed and validated for the identification and …

A high-performance liquid chromatography coupled to Fourier transform ion cyclotron
resonance mass spectrometry (HPLC-FT-ICR MS) method was developed to study the in …

The present study investigated the pharmacokinetics, excretion, and tissue distribution of
salidroside, a main active constituent in the roots of Rhodiola species. The plasma …

Ethnopharmacological relevance Salidroside (SA), a primary biologically active compound
in Fructus Ligustri Lucidi, has a definite effect on anti-aging, a physiological phenomenon …

Background Accumulating evidence suggests that Fructus Ligustri Lucidi (FLL) plays a
beneficial role in preventing the development of osteoporosis. However, the effects of FLL …

In the present work, the salidroside metabolite profile in rat urine was investigated, and
subsequently the metabolic pathways of salidroside were proposed. After administrations of …

Abstract Ethnopharmacological relevance Fructus Ligustri Lucidi (FLL) is an edible herb with
anti-osteoporotic activity, yet whether and how the aqueous extract of this herb affect calcium …

A method for the quantification of salidroside, a major biologically active compound in
Rhodiola, in rat plasma by on-line SPE LC/MS/MS in negative electrospray mode was …