A randomized trial of dual-acting bronchodilator AZD8871 for chronic obstructive pulmonary disease

D Singh, R Fuhr, L Jimenez… - American Journal of …, 2019 - atsjournals.org
Long-acting bronchodilators are recommended as maintenance therapy for chronic
obstructive pulmonary disease (COPD)(1). Dual therapy using long-acting muscarinic …

Double combination inhalers in COPD: How to get your head around this data.

D Singh - Respirology, 2018 - search.ebscohost.com
The development of inhalers containing both a longacting muscarinic antagonist (LAMA)
and a long-acting beta agonist (LABA) has increased the treatment options in chronic …

Dual LABA/LAMA bronchodilators in chronic obstructive pulmonary disease: why, when, and how

L Calzetta, MG Matera, P Rogliani… - Expert Review of …, 2018 - Taylor & Francis
Dual bronchodilation therapy is the cornerstone for the treatment of chronic obstructive
pulmonary disease (COPD)[1]. Combining a long-acting β2 adrenoceptor (β2-AR) agonist …

Safety considerations with dual bronchodilator therapy in COPD: an update

MG Matera, P Rogliani, L Calzetta, M Cazzola - Drug safety, 2016 - Springer
Combining a long-acting β 2-agonist (LABA) with a long-acting anti-muscarinic agent
(LAMA) provides synergistic benefit on airway smooth muscle relaxation, which may have …

Pharmacotherapy of LAMA/LABA inhaled therapy combinations for chronic obstructive pulmonary disease: a clinical overview

MG Matera, B Rinaldi, C Belardo… - Expert Review of Clinical …, 2022 - Taylor & Francis
Introduction Long-acting muscarinic receptor antagonist (LAMA)/β2-agonist (LABA)
combinations represent a significant improvement in the treatment of chronic obstructive …

Dual bronchodilator therapy with aclidinium bromide/formoterol fumarate for chronic obstructive pulmonary disease

T D'Urzo, JF Donohue, D Price… - Expert Review of …, 2015 - Taylor & Francis
Inhaled bronchodilator therapy is a mainstay of treatment for chronic obstructive pulmonary
disease (COPD). Despite the number and types of treatments available, the control of …

Comparative Effectiveness of Long‐Acting Beta2‐Agonist Combined with a Long‐Acting Muscarinic Antagonist or Inhaled Corticosteroid in Chronic Obstructive …

JC Samp, MJ Joo, GT Schumock… - … : The Journal of …, 2017 - Wiley Online Library
Introduction Several dual bronchodilator fixed‐dose inhaler medications were recently
approved for the treatment of chronic obstructive pulmonary disease (COPD). These …

Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease

DP Tashkin, GT Ferguson - Respiratory research, 2013 - Springer
Chronic obstructive pulmonary disease (COPD) represents a significant cause of global
morbidity and mortality, with a substantial economic impact. Recent changes in the Global …

Considerations for new dual-acting bronchodilator treatments for chronic obstructive pulmonary disease

J de Miguel-Díez, R Jiménez-García - Expert Opinion on …, 2014 - Taylor & Francis
Current guidelines recommend treatment with one or more bronchodilators for chronic
obstructive pulmonary disease (COPD) patients. Combination therapy with long-acting …

Long-acting bronchodilators for chronic obstructive pulmonary disease: which one (s), how, and when?

AG Mathioudakis, J Vestbo… - Clinics in Chest …, 2020 - chestmed.theclinics.com
Chronic obstructive pulmonary disease (COPD) is characterized by chronic respiratory
symptoms, such as breathlessness and chronic productive cough, limited exercise …