Background Complement activation has been associated with atherosclerosis,
atherosclerotic plaque destabilization and increased risk of cardiovascular events …

Acute coronary syndrome is an inflammatory disease, during which the complement
cascade is activated. We assessed the complement C3 and C4 concentration ratio (C3/C4 …

OBJECTIVE To determine the association of serum complement C1q levels with
cardiovascular outcomes among patients with acute coronary syndrome (ACS) undergoing …

Aims Complement activation occurs in atherosclerotic lesions, and particularly complement
component C5a exerts potent chemotactic and proinflammatory effects. However, it is yet …

Introduction Chemokines mediate recruitment and activation of leucocytes. Chemokine
ligand 18 (CCL18) is mainly expressed by monocytes/macrophages and dendritic cells. It is …

Clinical studies as well as animal models emphasized the importance of the complement
system in the pathogenesis of coronary atherosclerosis and cardiovascular diseases. Our …

Background CC chemokine ligands (CCLs) are elevated during acute coronary syndrome
(ACS) and correlate with secondary events. Their involvement in plaque inflammation led us …

The aim of this study was to determine whether complement C3 is an indicator of coronary
artery disease (CAD). We measured plasma C3 and CRP levels in 278 patients undergoing …

Low-grade inflammation is involved in endothelial dysfunction, atherosclerosis and
cardiovascular disease (CVD)[1]. The complement system is an ancient inducer of …

Background Acute myocardial infarction (AMI) is a potentially fatal condition, being a major
cause of death worldwide. Ischemia suffered during AMI causes tissue damage, leading to …