IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for
inducing IL-17 production in other human immune subsets remains incompletely …

In this report, we show that IL-17+ CD4+ and IL-17+ CD8+ T cells are largely found in lung
and digestive mucosa compartments in normal mice. Endogenous and exogenous IL-1 …

IL-15 is an important IL-2–related cytokine whose role in Th17 cell biology has not been fully
elucidated. In this study, we show that exogenous IL-15 decreased IL-17A production in …

Summary Th17 cells, CD4+ T cells that secrete interleukin-17 (IL-17), are pathogenic in
autoimmune diseases and their development and expansion is driven by the cytokines IL-6 …

IL-23 plays a critical role establishing inflammatory immunity and enhancing IL-17
production in vivo. However, an understanding of how it performs those functions has been …

IL-17A is produced from Th17 cells, and is involved in many autoimmune and inflammatory
diseases. IL-13R has not previously been reported to be functionally expressed on T cells; …

Th17 cells are a distinct lineage of effector CD4+ T cells characterized by their production of
interleukin (IL)-17. We demonstrate that Th17 cells also expressed IL-22, an IL-10 family …

IL-17 family cytokines are critical to host defense responses at cutaneous and mucosal
surfaces. Whereas IL-17A, IL-17F, and IL-17C induce overlapping inflammatory cascades to …

T‐helper 17 (Th17) cells are a newly discovered CD4+ helper T‐cell subset that produces
interleukin‐17A (IL‐17A) and IL‐17F. IL‐17A plays important roles in allergic responses …

Interleukin (IL) 25 (IL-17E), a distinct member of the IL-17 cytokine family, plays important
roles in evoking T helper type 2 (Th2) cell–mediated inflammation that features the …